Vaghi Matilde M, Luyckx Fabrice, Sule Akeem, Fineberg Naomi A, Robbins Trevor W, De Martino Benedetto
Department of Psychology, University of Cambridge, Cambridge CB2 3EB, UK; Behavioural and Clinical Neuroscience Institute (BCNI), University of Cambridge, Cambridge CB2 3EB, UK.
Department of Psychology, University of Cambridge, Cambridge CB2 3EB, UK; Department of Experimental Psychology, University of Oxford, Oxford OX2 6BW, UK.
Neuron. 2017 Oct 11;96(2):348-354.e4. doi: 10.1016/j.neuron.2017.09.006. Epub 2017 Sep 28.
Confidence and actions are normally tightly interwoven-if I am sure that it is going to rain, I will take an umbrella-therefore, it is difficult to understand their interplay. Stimulated by the ego-dystonic nature of obsessive-compulsive disorder (OCD), where compulsive actions are recognized as disproportionate, we hypothesized that action and confidence might be independently updated during learning. Participants completed a predictive-inference task designed to identify how action and confidence evolve in response to surprising changes in the environment. While OCD patients (like controls) correctly updated their confidence according to changes in the environment, their actions (unlike those of controls) mostly disregarded this knowledge. Therefore, OCD patients develop an accurate, internal model of the environment but fail to use it to guide behavior. Results demonstrated a novel dissociation between confidence and action, suggesting a cognitive architecture whereby confidence estimates can accurately track the statistic of the environment independently from performance.
信心和行动通常紧密交织——如果我确定要下雨，我会带把伞——因此，理解它们之间的相互作用很困难。受强迫症（OCD）自我不协调性质的启发，在强迫症中强迫行为被认为是不相称的，我们推测在学习过程中行动和信心可能会独立更新。参与者完成了一项预测推理任务，旨在确定行动和信心如何随着环境的意外变化而演变。虽然强迫症患者（与对照组一样）根据环境变化正确更新了他们的信心，但他们的行动（与对照组不同）大多忽略了这些信息。因此，强迫症患者建立了一个准确的环境内部模型，但未能用它来指导行为。结果表明信心和行动之间存在一种新的分离，这表明存在一种认知结构，即信心估计可以独立于表现准确跟踪环境统计信息。
