Corsello Michael A, Kim Junyong, Garg Neil K
Department of Chemistry and Biochemistry , University of California , Los Angeles , California 90095 , USA . Email:
Chem Sci. 2017 Sep 1;8(9):5836-5844. doi: 10.1039/c7sc01248a. Epub 2017 Jun 27.
Indole terpenoids comprise a large class of natural products with diverse structural topologies and a broad range of biological activities. Accordingly, indole terpenoids have and continue to serve as attractive targets for chemical synthesis. Many synthetic efforts over the past few years have focused on a subclass of this family, the indole diterpenoids. This minireview showcases the role indole diterpenoids have played in inspiring the recent development of clever synthetic strategies, and new chemical reactions.
吲哚萜类化合物是一大类天然产物,具有多样的结构拓扑和广泛的生物活性。因此,吲哚萜类化合物一直并将继续成为化学合成的有吸引力的目标。在过去几年中,许多合成工作都集中在这个家族的一个亚类,即吲哚二萜类化合物上。这篇小型综述展示了吲哚二萜类化合物在激发巧妙合成策略和新化学反应的近期发展中所起的作用。