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酒精使用、大麻使用以及酒精与大麻同时使用的感知急性效应报告差异。

Differences in reporting of perceived acute effects of alcohol use, marijuana use, and simultaneous alcohol and marijuana use.

作者信息

Lee Christine M, Cadigan Jennifer M, Patrick Megan E

机构信息

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.

出版信息

Drug Alcohol Depend. 2017 Nov 1;180:391-394. doi: 10.1016/j.drugalcdep.2017.08.029. Epub 2017 Sep 14.

Abstract

BACKGROUND

Although there are serious negative harms associated with simultaneous alcohol and marijuana (SAM) use, little is known about the self-reported acute effects of SAM use and how they may be similar to or different than effects experienced when using alcohol or marijuana only. The current study examines the perceived acute effects of SAM use, compared to using alcohol or marijuana only, as well as demographic and substance use predictors of overall SAM effects.

METHODS

Participants were a community sample of young adults ages 18-23 participating in a longitudinal study on social role transitions and substance use during young adulthood. Young adults who reported SAM use at least once in their lifetime were selected for the present analyses (N=315; mean age=21.42; 58% female) and reported the effects they experienced from typical alcohol use, marijuana use, and SAM use.

RESULTS

There were significant differences in the extent to which young adults perceived the effects depending on the substances used. Most effects (i.e., clumsy, confused, dizzy, difficulty concentrating) were rated strongest when engaging in SAM use, compared to typical alcohol or marijuana use alone. Feeling high and feeling marijuana effects were rated strongest when engaging in marijuana use alone compared to SAM use, but feeling drunk was greater during SAM use compared to alcohol use alone. Greater alcohol use and increased time spent high during typical SAM use were associated with greater overall SAM effects.

CONCLUSIONS

When young adults engage in SAM use they report experiencing greater negative physiological and cognitive effects.

摘要

背景

尽管同时使用酒精和大麻(SAM)会带来严重的负面危害,但对于自我报告的SAM使用急性影响以及这些影响与仅使用酒精或大麻时所经历的影响有何异同,人们知之甚少。本研究考察了与仅使用酒精或大麻相比,SAM使用的感知急性影响,以及总体SAM影响的人口统计学和物质使用预测因素。

方法

参与者是18至23岁的年轻成年人社区样本,他们参与了一项关于青年期社会角色转变和物质使用的纵向研究。本分析选取了一生中至少报告过一次SAM使用的年轻成年人(N = 315;平均年龄 = 21.42;58%为女性),并报告了他们从典型的酒精使用、大麻使用和SAM使用中所经历的影响。

结果

根据所使用的物质不同,年轻成年人对影响的感知程度存在显著差异。与单独使用典型酒精或大麻相比,大多数影响(即笨拙、困惑、头晕、注意力不集中)在使用SAM时被评为最强。单独使用大麻时,“兴奋感”和“感觉到大麻的影响”被评为比使用SAM时更强,但与单独使用酒精相比,使用SAM时“醉酒感”更强。在典型的SAM使用中,更多的酒精使用和更长时间的“兴奋”与更强的总体SAM影响相关。

结论

当年轻成年人使用SAM时,他们报告经历了更大的负面生理和认知影响。

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