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A histone H1 protein in sea urchins is encoded by a poly(A)+ mRNA.

作者信息

Lieber T, Angerer L M, Angerer R C, Childs G

机构信息

Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461.

出版信息

Proc Natl Acad Sci U S A. 1988 Jun;85(12):4123-7. doi: 10.1073/pnas.85.12.4123.

DOI:10.1073/pnas.85.12.4123
PMID:2898141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC280378/
Abstract

Typical histone genes lack intervening sequences and encode small mRNAs (400-800 nucleotides) with short leader and trailer regions. Most histone mRNAs are not polyadenylylated but rather terminate in a highly conserved stem and loop structure. The early, late, and testis-specific histone genes of sea urchins, described to date, have this typical histone gene structure. We have identified an unusual H1 gene, H1-delta, in sea urchins that encodes a poly(A)+ mRNA. This mRNA is one of a group of polyadenylylated transcripts homologous with H1 gene probes. The sequence of H1-delta had been determined. H1-delta encodes a different H1 protein. Although the temporal expression of H1-delta mRNA is similar to that of other late H1 (beta and gamma) mRNAs, its spatial distribution at the time of maximal accumulation is distinct and confirms that H1-delta is regulated differently than other H1 genes.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9473/280378/46aea1d9a05c/pnas00264-0020-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9473/280378/b9b8c9ac6fe5/pnas00264-0018-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9473/280378/614346955c64/pnas00264-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9473/280378/46aea1d9a05c/pnas00264-0020-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9473/280378/b9b8c9ac6fe5/pnas00264-0018-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9473/280378/614346955c64/pnas00264-0019-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9473/280378/46aea1d9a05c/pnas00264-0020-a.jpg

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1
A histone H1 protein in sea urchins is encoded by a poly(A)+ mRNA.
Proc Natl Acad Sci U S A. 1988 Jun;85(12):4123-7. doi: 10.1073/pnas.85.12.4123.
2
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3
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Mol Cell Biol. 1997 Mar;17(3):1189-200. doi: 10.1128/MCB.17.3.1189.
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Polyadenylylation of sea urchin histone RNA sequences in transfected COS cells.转染的COS细胞中海胆组蛋白RNA序列的聚腺苷酸化
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5
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Nonallelic histone gene clusters of individual sea urchins (Lytechinus pictus): mapping of homologies in coding and spacer DNA.单个海胆（彩绘海胆）的非等位组蛋白基因簇：编码DNA和间隔DNA中的同源性图谱
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Both basal and ontogenic promoter elements affect the timing and level of expression of a sea urchin H1 gene during early embryogenesis.
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Leader sequences of Strongylocentrotus purpuratus histone mRNAs start at a unique heptanucleotide common to all five histone genes.紫球海胆组蛋白mRNA的前导序列始于所有五个组蛋白基因共有的一个独特七核苷酸。
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引用本文的文献

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Common evolutionary origin and birth-and-death process in the replication-independent histone H1 isoforms from vertebrate and invertebrate genomes.脊椎动物和无脊椎动物基因组中与复制无关的组蛋白H1亚型的共同进化起源和生死过程。
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本文引用的文献

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The structure of histone H1 and its location in chromatin.组蛋白H1的结构及其在染色质中的位置。
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Yeast histone mRNA is polyadenylated.酵母组蛋白信使核糖核酸是聚腺苷酸化的。
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The five cleavage-stage (CS) histones of the sea urchin are encoded by a maternally expressed family of replacement histone genes: functional equivalence of the CS H1 and frog H1M (B4) proteins.海胆的五种卵裂期（CS）组蛋白由一个母源表达的替代组蛋白基因家族编码：CS H1和青蛙H1M（B4）蛋白的功能等效性。
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The vertebrate linker histones H1 zero, H5, and H1M are descendants of invertebrate "orphon" histone H1 genes.脊椎动物的连接组蛋白H1零、H5和H1M是无脊椎动物“孤儿”组蛋白H1基因的后代。
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Basal expression of the histone H5 gene is controlled by positive and negative cis-acting sequences.组蛋白H5基因的基础表达受正向和负向顺式作用序列的控制。
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Nucleic Acids Res. 1989 Apr 25;17(8):3057-63. doi: 10.1093/nar/17.8.3057.
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Histone and histone gene compilation and alignment update.组蛋白及组蛋白基因汇编与比对更新。
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A genomic clone encoding a novel proliferation-dependent histone H2A.1 mRNA enriched in the poly(A)+ fraction.一个编码新型增殖依赖性组蛋白H2A.1 mRNA的基因组克隆，该mRNA在聚腺苷酸加尾（poly(A)+）组分中富集。
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The histone H1 complements of dividing and nondividing cells of the mouse.小鼠分裂细胞和非分裂细胞的组蛋白H1互补物。
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Detection of mrnas in sea urchin embryos by in situ hybridization using asymmetric RNA probes.使用不对称RNA探针通过原位杂交检测海胆胚胎中的mRNA。
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Genomic organization of the genes coding for the six main histones of the chicken: complete sequence of the H5 gene.鸡的六种主要组蛋白编码基因的基因组组织：H5基因的完整序列
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Molecular biology of the sea urchin embryo.海胆胚胎的分子生物学
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Multiple, independently regulated, polyadenylated messages for histone H3 and H4 in Tetrahymena.四膜虫中组蛋白H3和H4的多个独立调控的多聚腺苷酸化信使RNA
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