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根除脊髓灰质炎活动对常规免疫的影响:来自埃塞俄比亚索马里地区2013年疫情应对的经验教训。

Effects of polio eradication activities on routine immunization: lessons from the 2013 outbreak response in Somali region of Ethiopia.

作者信息

Tafesse Belete, Tekle Ephrem, Wondwossen Liya, Bogale Mengistu, Fiona Braka, Nsubuga Peter, Tomas Karengera, Kassahun Aron, Kathleen Gallagher, Teka Aschalew

机构信息

World Health Organization, Ethiopia.

Ministry of Health, Ethiopia.

出版信息

Pan Afr Med J. 2017 Jun 9;27(Suppl 2):4. doi: 10.11604/pamj.supp.2017.27.2.10569. eCollection 2017.

Abstract

INTRODUCTION

Ethiopia experienced several WPV importations with a total of 10 WPV1 cases confirmed during the 2013 outbreak alone before it is closed in 2015. We evaluated supplemental immunization activities (SIAs), including lessons learned for their effect on the routine immunization program during the 2013 polio outbreak in Somali regional state.

METHODS

We used descriptive study to review documents and analyse routine health information system reports from the polio outbreak affected Somali regional state.

RESULTS

All data and technical reports of the 15 rounds of polio SIAs from June 2013 through June 2015 and routine immunization coverages for DPT-Hib-HepB 3 and measles were observed. More than 93% of the SIAs were having administrative coverage above 95%. The trend of routine immunization for the two antigens, over the five years (2011 through 2015) did not show a consistent pattern against the number of SIAs. Documentations showed qualitative positive impacts of the SIAs strengthening the routine immunization during all courses of the campaigns.

CONCLUSION

The quantitative impact of polio SIAs on routine immunization remained not so impressive in this study. Clear planning, data consistencies and completeness issues need to be cleared for the impact assessment in quantitative terms, in polio legacy planning as well as for the introduction of injectable polio vaccine through the routine immunization.

摘要

引言

埃塞俄比亚经历了几次野生脊灰病毒输入事件,仅在2013年疫情爆发期间就确诊了10例I型野生脊灰病毒病例,随后该国于2015年实现无脊灰。我们评估了补充免疫活动(SIAs),包括在2013年索马里州脊髓灰质炎疫情期间补充免疫活动对常规免疫规划影响的经验教训。

方法

我们采用描述性研究方法,回顾文件并分析受脊髓灰质炎疫情影响的索马里州的常规卫生信息系统报告。

结果

观察了2013年6月至2015年6月期间15轮脊髓灰质炎补充免疫活动的所有数据和技术报告,以及白喉、百日咳、破伤风、B型流感嗜血杆菌结合疫苗、乙肝疫苗3剂次和麻疹疫苗的常规免疫覆盖率。超过93%的补充免疫活动行政覆盖率高于95%。在2011年至2015年的五年间,两种抗原的常规免疫趋势与补充免疫活动的次数并未呈现出一致的模式。文件显示,补充免疫活动在所有活动过程中对加强常规免疫具有定性的积极影响。

结论

在本研究中,脊髓灰质炎补充免疫活动对常规免疫的定量影响仍然不太显著。在脊髓灰质炎遗留规划以及通过常规免疫引入注射用脊髓灰质炎疫苗方面,需要明确规划、解决数据一致性和完整性问题,以便进行定量的影响评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d01c/5619919/1dbdc79fde1b/PAMJ-SUPP-27-2-04-g001.jpg

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