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不同表面活性剂的甲氨基阿维菌素苯甲酸盐缓释微球的合成与表征

Synthesis and characterization of emamectin-benzoate slow-release microspheres with different surfactants.

作者信息

Wang Yan, Wang Anqi, Wang Chunxin, Cui Bo, Sun Changjiao, Zhao Xiang, Zeng Zhanghua, Shen Yue, Gao Fei, Liu Guoqiang, Cui Haixin

机构信息

Institute of Environment and Sustainable Development in Agriculture, Chinese Academic of Agriculture Sciences, Beijing, 100081, China.

Nano Agricultural Research Center, Chinese Academic of Agriculture Sciences, Beijing, 100081, China.

出版信息

Sci Rep. 2017 Oct 6;7(1):12761. doi: 10.1038/s41598-017-12724-6.

Abstract

Pesticide slow-release formulations provide a way to increase the efficiency of active components by reducing the amount of pesticide that needs to be applied. Slow-release formulations also increase the stability and prolong the control effect of photosensitive pesticides. Surfactants are an indispensable part of pesticide formulations, and the choice of surfactant can strongly affect formulation performance. In this study, emamectin-benzoate (EMB) slow-release microspheres were prepared by the microemulsion polymerization method. We explored the effect of different surfactants on the particle size and dispersity of EMB in slow-release microspheres. The results indicated that the samples had uniform spherical shapes with an average diameter of 320.5 ±5.24 nm and good dispersity in the optimal formulation with the polymeric stabilizer polyvinyl alcohol (PVA) and composite non-ionic surfactant polyoxyethylene castor oil (EL-40). The optimal EMB pesticide slow-release microspheres had excellent anti-photolysis performance, stability, controlled release properties, and good leaf distribution. These results demonstrated that EMB slow-release microspheres are an attractive candidate for improving pesticide efficacy and prolonging the control effect of EMB in the environment.

摘要

农药缓释制剂提供了一种通过减少农药施用量来提高活性成分效率的方法。缓释制剂还能提高光敏农药的稳定性并延长其防治效果。表面活性剂是农药制剂中不可或缺的一部分,表面活性剂的选择会强烈影响制剂性能。在本研究中,通过微乳液聚合法制备了甲氨基阿维菌素苯甲酸盐(EMB)缓释微球。我们探究了不同表面活性剂对EMB在缓释微球中的粒径和分散性的影响。结果表明,在含有聚合物稳定剂聚乙烯醇(PVA)和复合非离子表面活性剂聚氧乙烯蓖麻油(EL-40)的最佳配方中,样品呈均匀球形,平均直径为320.5±5.24 nm,且具有良好的分散性。最佳的EMB农药缓释微球具有优异的抗光解性能、稳定性、控释性能以及良好的叶片分布。这些结果表明,EMB缓释微球是提高农药效果和延长EMB在环境中防治效果的一个有吸引力的候选物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b22/5630577/44e637f901a8/41598_2017_12724_Fig1_HTML.jpg

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