The IgH 3' regulatory region super-enhancer does not control IgA class switch recombination in the B1 lineage.
作者信息
Issaoui Hussein, Ghazzaui Nour, Saintamand Alexis, Carrion Claire, Oblet Christelle, Denizot Yves
机构信息
CNRS UMR 7276, CRIBL, Université de Limoges, Limoges, France.
出版信息
Cell Mol Immunol. 2018 Mar;15(3):289-291. doi: 10.1038/cmi.2017.103. Epub 2017 Oct 9.
Abstract
摘要
相似文献
1
The IgH 3' regulatory region super-enhancer does not control IgA class switch recombination in the B1 lineage.免疫球蛋白重链（IgH）3'调控区超级增强子并不控制B1细胞系中的IgA类别转换重组。
Cell Mol Immunol. 2018 Mar;15(3):289-291. doi: 10.1038/cmi.2017.103. Epub 2017 Oct 9.
2
3'RR and 5'E immunoglobulin heavy chain enhancers are independent engines of locus remodeling.3'RR和5'E免疫球蛋白重链增强子是基因座重塑的独立引擎。
Cell Mol Immunol. 2019 Feb;16(2):198-200. doi: 10.1038/s41423-018-0171-3. Epub 2018 Oct 10.
3
Deletion of the immunoglobulin heavy chain 3' regulatory region super-enhancer affects somatic hypermutation in B1 B cells.免疫球蛋白重链3'调控区超级增强子的缺失影响B1 B细胞中的体细胞超突变。
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4
Interaction between the immunoglobulin heavy chain 3' regulatory region and the IgH transcription unit during B cell differentiation.B 细胞分化过程中免疫球蛋白重链 3' 调控区与 IgH 转录单元的相互作用。
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The IgH locus 3' cis-regulatory super-enhancer co-opts AID for allelic transvection.免疫球蛋白重链基因座3'顺式调控超级增强子借助活化诱导胞嘧啶脱氨酶实现等位基因转位作用。
Oncotarget. 2017 Feb 21;8(8):12929-12940. doi: 10.18632/oncotarget.14585.
6
Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells.由3'Igk增强子介导的Igk和Igh免疫球蛋白基因座之间的关联诱导前B细胞中Igh基因座的“去收缩”。
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Transcription of a productively rearranged Ig VDJC alpha does not require the presence of HS4 in the IgH 3' regulatory region.有功能重排的Ig VDJCα的转录并不需要IgH 3'调控区中HS4的存在。
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Complex biallelic IGH rearrangements in IgM-expressing Z-138 cell line: Involvement of downstream immunoglobulin class switch recombination.表达IgM的Z-138细胞系中的复杂双等位基因IGH重排：下游免疫球蛋白类别转换重组的参与
Genes Chromosomes Cancer. 2005 Feb;42(2):164-9. doi: 10.1002/gcc.20132.
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Class switch recombination junctions are not affected by the absence of the immunoglobulin heavy chain E enhancer.类别转换重组连接不受免疫球蛋白重链E增强子缺失的影响。
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The Eμ enhancer region influences H chain expression and B cell fate without impacting IgVH repertoire and immune response in vivo.Eμ 增强子区域影响 H 链表达和 B 细胞命运，而不影响体内 IgVH 库和免疫反应。
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Long-Range Control of Class Switch Recombination by Transcriptional Regulatory Elements.转录调控元件对类别转换重组的远程控制。
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2
V(D)J recombination, somatic hypermutation and class switch recombination of immunoglobulins: mechanism and regulation.免疫球蛋白的 V(D)J 重组、体细胞高频突变和类别转换重组：机制和调控。
Immunology. 2020 Jul;160(3):233-247. doi: 10.1111/imm.13176. Epub 2020 Feb 27.
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A novel regulatory region controls IgH locus transcription and switch recombination to a subset of isotypes.一个新的调控区域控制免疫球蛋白重链（IgH）基因座的转录以及向一部分同种型的类别转换重组。
Cell Mol Immunol. 2019 Nov;16(11):887-889. doi: 10.1038/s41423-019-0267-4. Epub 2019 Aug 5.
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3'RR and 5'E immunoglobulin heavy chain enhancers are independent engines of locus remodeling.3'RR和5'E免疫球蛋白重链增强子是基因座重塑的独立引擎。
Cell Mol Immunol. 2019 Feb;16(2):198-200. doi: 10.1038/s41423-018-0171-3. Epub 2018 Oct 10.
5
The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination.染色质读码子 ZMYND8 通过调控 Igh 增强子促进免疫球蛋白类别转换重组。
Mol Cell. 2018 Nov 15;72(4):636-649.e8. doi: 10.1016/j.molcel.2018.08.042. Epub 2018 Oct 4.
6
Uracil-DNA glycosylase is not implicated in the choice of the DNA repair pathway during B-cell class switch recombination.尿嘧啶-DNA糖基化酶在B细胞类别转换重组过程中与DNA修复途径的选择无关。
Cell Mol Immunol. 2019 Jan;16(1):93-95. doi: 10.1038/s41423-018-0034-y. Epub 2018 May 7.
7
High-throughput sequencing reveals similar molecular signatures for class switch recombination junctions for the γ and α isotypes.高通量测序揭示了γ和α同种型类别转换重组连接的相似分子特征。
Cell Mol Immunol. 2019 Jan;16(1):90-92. doi: 10.1038/s41423-018-0025-z. Epub 2018 Mar 23.
8
The H2B deubiquitinase Usp22 promotes antibody class switch recombination by facilitating non-homologous end joining.H2B去泛素化酶Usp22通过促进非同源末端连接来促进抗体类别转换重组。
Nat Commun. 2018 Mar 8;9(1):1006. doi: 10.1038/s41467-018-03455-x.
9
The immunoglobulin heavy chain 3' regulatory region superenhancer controls mouse B1 B-cell fate and late VDJ repertoire diversity.免疫球蛋白重链 3'调控区超级增强子控制小鼠 B1 B 细胞命运和晚期 VDJ 库多样性。
Blood Adv. 2018 Feb 13;2(3):252-262. doi: 10.1182/bloodadvances.2017014423.
本文引用的文献
1
IgD class switch recombination is not controlled through the immunoglobulin heavy chain 3' regulatory region super-enhancer.IgD类别转换重组不受免疫球蛋白重链3'调控区超级增强子的控制。
Cell Mol Immunol. 2017 Oct;14(10):871-874. doi: 10.1038/cmi.2017.81. Epub 2017 Sep 4.
2
E and 3'RR IgH enhancers show hierarchic unilateral dependence in mature B-cells.E 和 3'RR IgH 增强子在成熟 B 细胞中表现出层次化的单侧依赖性。
Sci Rep. 2017 Mar 27;7(1):442. doi: 10.1038/s41598-017-00575-0.
3
Class-Switch Recombination in the Absence of the IgH 3' Regulatory Region.缺失IgH 3'调控区时的类别转换重组
J Immunol. 2016 Oct 1;197(7):2930-5. doi: 10.4049/jimmunol.1600530. Epub 2016 Aug 24.
4
Evolutionary implication of B-1 lineage cells from innate to adaptive immunity.B-1细胞系从固有免疫到适应性免疫的进化意义。
Mol Immunol. 2016 Jan;69:123-30. doi: 10.1016/j.molimm.2015.10.014. Epub 2015 Nov 10.
5
The role of B-1 cells in inflammation.B-1细胞在炎症中的作用。
Immunol Res. 2015 Dec;63(1-3):153-66. doi: 10.1007/s12026-015-8708-3.
6
B cells in the aging immune system: time to consider B-1 cells.衰老免疫系统中的B细胞：是时候关注B-1细胞了。
Ann N Y Acad Sci. 2015 Dec;1362(1):176-87. doi: 10.1111/nyas.12825. Epub 2015 Jul 20.
7
Antibody-independent functions of B cells: a focus on cytokines.B 细胞的抗体非依赖性功能：聚焦细胞因子。
Nat Rev Immunol. 2015 Jul;15(7):441-51. doi: 10.1038/nri3857. Epub 2015 Jun 12.
8
Elucidation of IgH 3' region regulatory role during class switch recombination via germline deletion.通过胚系缺失阐明 IgH 3' 区域在类别转换重组过程中的调控作用。
Nat Commun. 2015 May 11;6:7084. doi: 10.1038/ncomms8084.
9
Elucidation of the enigmatic IgD class-switch recombination via germline deletion of the IgH 3' regulatory region.通过缺失 IgH 3'调控区的胚系删除来阐明神秘的 IgD 类别转换重组。
J Exp Med. 2014 May 5;211(5):975-85. doi: 10.1084/jem.20131385. Epub 2014 Apr 21.
10
An intrinsic propensity of murine peritoneal B1b cells to switch to IgA in presence of TGF-β and retinoic acid.在 TGF-β 和维甲酸存在的情况下，小鼠腹腔 B1b 细胞向 IgA 转换的内在倾向。
PLoS One. 2013 Dec 6;8(12):e82121. doi: 10.1371/journal.pone.0082121. eCollection 2013.
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