• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

玻璃体腔内注射组织型纤溶酶原激活剂后行八氟丙烷气体注射治疗视网膜内界膜下出血。

Sub-internal limiting membrane hemorrhage treated with intravitreal tissue plasminogen activator followed by octafluoropropane gas injection.

作者信息

Chou Yu-Kang, Huang Yi-Ming, Lin Po-Kang

机构信息

Medical Department, National Yang-Ming University, Taipei, Taiwan.

Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan.

出版信息

Taiwan J Ophthalmol. 2015 Oct-Dec;5(4):198-201. doi: 10.1016/j.tjo.2014.10.006. Epub 2014 Dec 4.

DOI:10.1016/j.tjo.2014.10.006
PMID:29018700
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5602142/
Abstract

Sub-internal limiting membrane (sub-ILM) hemorrhage is a relatively rare disease which is associated with different etiologies and often leads to loss of visual acuity. We report two cases of sub-ILM hemorrhage, both confirmed by optical coherence tomography (OCT) and treated with an intravitreal injection of tissue plasminogen activator (tPA) followed by an octafluoropropane (CF) pneumopexy and a strict postoperative prone positioning. The hemorrhage was totally resolved and complete visual recovery was achieved in both cases. We found tPA hemolysis with CF pneumopexy to be a safe and effective method for treating sub-ILM hemorrhage.

摘要

内界膜下（sub-ILM）出血是一种相对罕见的疾病，其病因各异，常导致视力丧失。我们报告两例内界膜下出血病例，均经光学相干断层扫描（OCT）确诊，并接受玻璃体内注射组织纤溶酶原激活剂（tPA）治疗，随后进行八氟丙烷（CF）气体视网膜固定术及严格的术后俯卧位。两例患者出血均完全吸收，视力完全恢复。我们发现tPA联合CF气体视网膜固定术是治疗内界膜下出血的一种安全有效的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d08/5602142/7e27683cafe0/TJO-5-198-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d08/5602142/e3e3669a6a6e/TJO-5-198-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d08/5602142/7e27683cafe0/TJO-5-198-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d08/5602142/e3e3669a6a6e/TJO-5-198-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d08/5602142/7e27683cafe0/TJO-5-198-g002.jpg

相似文献

1
Sub-internal limiting membrane hemorrhage treated with intravitreal tissue plasminogen activator followed by octafluoropropane gas injection.玻璃体腔内注射组织型纤溶酶原激活剂后行八氟丙烷气体注射治疗视网膜内界膜下出血。
Taiwan J Ophthalmol. 2015 Oct-Dec;5(4):198-201. doi: 10.1016/j.tjo.2014.10.006. Epub 2014 Dec 4.
2
Intravitreal tissue plasminogen activator, perfluoropropane (C3F8), and ranibizumab or photodynamic therapy for submacular hemorrhage secondary to wet age-related macular degeneration.眼内组织型纤溶酶原激活物、全氟丙烷（C3F8）以及雷珠单抗或光动力疗法治疗湿性年龄相关性黄斑变性继发的黄斑下出血。
Retina. 2013 Apr;33(4):846-53. doi: 10.1097/IAE.0b013e318271f278.
3
Pneumatic displacement with perfluoropropane gas and intravitreal tissue plasminogen activator for subretinal subfoveal hemorrhage after focal laser photocoagulation in central serous chorioretinopathy.全氟丙烷气体气动置换联合玻璃体内注射组织型纤溶酶原激活剂治疗中心性浆液性脉络膜视网膜病变局灶性激光光凝后视网膜下黄斑区出血
Case Rep Ophthalmol Med. 2014;2014:592746. doi: 10.1155/2014/592746. Epub 2014 Nov 17.
4
Treatment of multilevel macular hemorrhage secondary to retinal arterial macroaneurysm with submacular tissue plasminogen activator.用黄斑下组织纤溶酶原激活剂治疗视网膜动脉大动脉瘤继发的多层面黄斑出血。
Eur J Ophthalmol. 2012 Nov-Dec;22(6):1026-31. doi: 10.5301/ejo.5000140. Epub 2012 Mar 20.
5
Pneumatic Displacement of a Dense Sub-inner Limiting Membrane Pre-macular Hemorrhage in Dengue Maculopathy: A Novel Treatment Approach.登革热黄斑病变中致密的内界膜下黄斑前出血的气体置换：一种新的治疗方法。
Turk J Ophthalmol. 2019 Feb 28;49(1):51-54. doi: 10.4274/tjo.galenos.2018.94103.
6
Intravitreal Tissue Plasminogen Activator, Ranibizumab, and Gas Injection for Submacular Hemorrhage in Polypoidal Choroidal Vasculopathy.眼内组织型纤溶酶原激活物、雷珠单抗联合气体注射治疗息肉样脉络膜血管病变伴黄斑下出血
Ophthalmology. 2016 Jun;123(6):1278-86. doi: 10.1016/j.ophtha.2016.01.035. Epub 2016 Mar 2.
7
TISSUE PLASMINOGEN ACTIVATOR FOR SUBFOVEAL HEMORRHAGE DUE TO AGE-RELATED MACULAR DEGENERATION: Comparison of 3 Treatment Modalities.组织型纤溶酶原激活剂治疗年龄相关性黄斑变性所致黄斑下出血：三种治疗方式的比较
Retina. 2016 Oct;36(10):1860-5. doi: 10.1097/IAE.0000000000001030.
8
Sub-internal limiting membrane hemorrhage as an unusual presentation of polypoidal choroidal vasculopathy.视网膜内界膜下出血作为息肉样脉络膜血管病变的一种不寻常表现。
Oman J Ophthalmol. 2021 Feb 27;14(1):56-59. doi: 10.4103/ojo.OJO_310_2020. eCollection 2021 Jan-Apr.
9
Late spectral-domain optical coherence tomography findings in sub-internal limiting membrane hemorrhage.
Retin Cases Brief Rep. 2013 Summer;7(3):276-7. doi: 10.1097/ICB.0b013e31828eefbd.
10
[Clinical results of intravitreal administration of tissue-type plasminogen activator (tPA) and gas for removal of subretinal hemorrhage in senile macular degeneration].玻璃体内注射组织型纤溶酶原激活剂（tPA）联合气体治疗老年黄斑变性视网膜下出血的临床结果
Klin Monbl Augenheilkd. 2000 Jan;216(1):33-9. doi: 10.1055/s-2000-10513.

引用本文的文献

1
Characterization of retinal hemorrhages delimited by the internal limiting membrane.视网膜内界膜界定的视网膜出血特征。
Indian J Ophthalmol. 2024 Jan 1;72(Suppl 1):S3-S10. doi: 10.4103/IJO.IJO_266_23. Epub 2023 Dec 22.
2
Bilateral sub-internal limiting membrane hemorrhage in a COVID-19 patient.一名新冠肺炎患者出现双侧内界膜下出血。
Indian J Ophthalmol. 2022 Aug;70(8):3141-3142. doi: 10.4103/ijo.IJO_337_22.
3
A Case of Acute Promyelocytic Leukemia With Retinal Hemorrhages Beneath Internal Limiting Membrane During Clinical Remission.

本文引用的文献

1
Long-term evolution of Valsalva retinopathy: a case series.瓦尔萨尔瓦视网膜病变的长期演变：病例系列
J Med Case Rep. 2012 Oct 10;6:346. doi: 10.1186/1752-1947-6-346.
2
Pneumatic displacement of submacular hemorrhage with or without tissue plasminogen activator.气动力性推动黄斑下出血伴或不伴组织型纤溶酶原激活物。
Graefes Arch Clin Exp Ophthalmol. 2011 Aug;249(8):1153-7. doi: 10.1007/s00417-011-1649-1. Epub 2011 Mar 29.
3
Spectral-domain optical coherence tomography following Nd:YAG laser membranotomy in valsalva retinopathy.
临床缓解期急性早幼粒细胞白血病伴内界膜下视网膜出血1例
Cureus. 2021 Feb 17;13(2):e13387. doi: 10.7759/cureus.13387.
4
Bilateral and multiple sub-internal limiting membrane hemorrhages in a familial retinal arteriolar tortuosity patient by Valsalva-like mechanism: an observational case report.家族性视网膜小动脉迂曲患者 Valsalva 样机制致双侧多发内界膜下出血：观察性病例报告。
BMC Ophthalmol. 2020 Apr 15;20(1):151. doi: 10.1186/s12886-020-01413-0.
5
Spontaneous Macular Hole Closure after Valsalva Retinopathy and Nd:YAG Laser Treatment.瓦氏视网膜病变及钕钇铝石榴石激光治疗后黄斑裂孔的自发闭合
Case Rep Ophthalmol Med. 2018 Aug 23;2018:1782847. doi: 10.1155/2018/1782847. eCollection 2018.
6
[Laser membranotomy in the management of acute premacular hemorrhage : Case report and overview on the approach].[激光膜切开术治疗急性黄斑前出血：病例报告及治疗方法概述]
Ophthalmologe. 2018 Dec;115(12):1059-1065. doi: 10.1007/s00347-018-0692-2.
瓦氏视网膜病变中Nd:YAG激光膜切开术后的频域光学相干断层扫描
Ophthalmic Surg Lasers Imaging. 2011 May-Jun;42(3):222-8. doi: 10.3928/15428877-20110224-01. Epub 2011 Mar 3.
4
Optical coherence tomography features of sub-internal limiting membrane hemorrhage and temporary premacular cavity following Nd-YAG laser membranotomy in Valsalva retinopathy.瓦尔萨尔瓦视网膜病变患者经Nd-YAG激光膜切开术后内界膜下出血及黄斑前临时腔隙的光学相干断层扫描特征
Jpn J Ophthalmol. 2008 Nov-Dec;52(6):513-515. doi: 10.1007/s10384-008-0592-0. Epub 2008 Dec 17.
5
Sub-inner limiting membrane haemorrhage: causes and treatment with vitrectomy.视网膜内界膜下出血：病因及玻璃体切除术治疗
Br J Ophthalmol. 2007 Jul;91(7):869-72. doi: 10.1136/bjo.2006.109132. Epub 2007 Jan 17.
6
Management of subretinal macular haemorrhage by direct administration of tissue plasminogen activator.通过直接注射组织型纤溶酶原激活剂治疗黄斑下视网膜出血
Br J Ophthalmol. 2006 Apr;90(4):429-31. doi: 10.1136/bjo.2005.085001.
7
Is the location of valsalva hemorrhages submembranous or subhyaloidal?瓦尔萨尔瓦出血的位置是在膜下还是玻璃膜下？
Am J Ophthalmol. 2006 Jan;141(1):231; author reply 231-2. doi: 10.1016/j.ajo.2005.08.040.
8
Prevalence of retinopathy in patients with anemia or thrombocytopenia.贫血或血小板减少症患者视网膜病变的患病率。
Eur J Haematol. 2001 Oct;67(4):238-44. doi: 10.1034/j.1600-0609.2001.00539.x.
9
Treating subretinal hemorrhage with tissue plasminogen activator.
Arch Ophthalmol. 2002 Jan;120(1):102-3; author reply 203.
10
Treatment of subhyaloid haemorrhage with intravitreal tissue plasminogen activator and C3F8 gas injection.玻璃体腔内注射组织型纤溶酶原激活剂及注入C3F8气体治疗玻璃膜下出血
Br J Ophthalmol. 2000 Nov;84(11):1329-30. doi: 10.1136/bjo.84.11.1318l.