Department of Physiology, Biophysics and Neuroscience, Centro de Investigacion y de Estudios Avanzados del IPN, Mexico; and.
Neuroplasticity and Behavior Unit, Laboratory of Neurosciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.
Physiology (Bethesda). 2017 Nov;32(6):410-424. doi: 10.1152/physiol.00017.2017.
Exercise is a simple intervention that profoundly benefits cognition. In rodents, running increases neurogenesis in the hippocampus, a brain area important for memory. We describe the dynamic changes in new neuron number and afferent connections throughout their maturation. We highlight the effects of exercise on the neurotransmitter systems involved, with a focus on the role of glutamate and acetylcholine in the initial development of new neurons in the adult brain.
运动是一种简单的干预措施，对认知有深远的益处。在啮齿动物中，跑步会增加海马体中的神经发生，海马体是大脑中对记忆很重要的区域。我们描述了新神经元数量和传入连接在整个成熟过程中的动态变化。我们强调了运动对涉及的神经递质系统的影响，重点关注谷氨酸和乙酰胆碱在成年大脑中新神经元初始发育中的作用。
