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人参皂苷Rg12，一种从根部提取的新型达玛烷型三萜皂苷。

Ginsenoside Rg12, a new dammarane-type triterpene saponin from root.

作者信息

Lee Dong Gu, Lee Jaemin, Cho Ik-Hyun, Kim Hak-Jae, Lee Sang-Won, Kim Young-Ock, Park Chun-Gun, Lee Sanghyun

机构信息

Department of Integrative Plant Science, Chung-Ang University, Anseong, Republic of Korea.

Department of Convergence Medical Science, Brain Korea 21 Plus Program, and Institute of Korean Medicine, College of Oriental Medicine, Kyung Hee University, Seoul, Republic of Korea.

出版信息

J Ginseng Res. 2017 Oct;41(4):531-533. doi: 10.1016/j.jgr.2016.10.002. Epub 2016 Oct 11.

DOI:10.1016/j.jgr.2016.10.002
PMID:29021700
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5628326/
Abstract

BACKGROUND

has been used as Korean medicine for various diseases. It has antioxidant, hypotensive, sedative, analgesic, and endocrine activities. Dammarane-type triterpenes from the plant have various beneficial effects.

METHODS

A dammarane-type triterpene saponin was isolated from root through chromatography such as repeated column chromatography and medium pressure liquid chromatography.

RESULTS AND CONCLUSION

New dammarane-type triterpene saponin was isolated for the first time from nature. The structure was elucidated as ginsenoside Rg12 () based on spectral data. There may be good materials from for the development of industrial applications such as nutraceutical, pharmaceutical, and cosmeceutical purposes.

摘要

背景

已被用作治疗各种疾病的韩药。它具有抗氧化、降血压、镇静、止痛和内分泌活性。该植物中的达玛烷型三萜具有多种有益作用。

方法

通过反复柱色谱和中压液相色谱等色谱法从根部分离出一种达玛烷型三萜皂苷。

结果与结论

首次从自然界中分离出新型达玛烷型三萜皂苷。根据光谱数据，其结构被鉴定为人参皂苷Rg12（）。对于营养保健品、药品和化妆品等工业应用的开发而言，可能存在来自的优质材料。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce36/5628326/22be34a75dc7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce36/5628326/22be34a75dc7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce36/5628326/22be34a75dc7/gr1.jpg

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