Industrial and Systems Engineering, Virginia Tech, Blacksburg, Virginia (Dr Kim, Dr Nussbaum); Department of Radiology (Dr Laurienti); Department of Biostatistical Science (Dr Chen); Department of Epidemiology and Prevention (Dr Quandt), Division of Public Health Sciences; Department of Environmental and Occupational Health, Rollins School of Public Health of Emory University, Atlanta, Georgia (Dr Barr); and Department of Family and Community Medicine (Dr Arcury), Center for Worker Health, Wake Forest School of Medicine, Winston-Salem, North Carolina.
J Occup Environ Med. 2018 Feb;60(2):174-179. doi: 10.1097/JOM.0000000000001194.
Apply a data-driven approach to explore associations between postural balance and pesticide exposure among Latino farmworkers and non-farmworkers.
Lasso-regularized, generalized linear models were used to examine associations between postural control measures in four experimental conditions (2 visual × 2 cognitive difficulty) and dialkylphosphate (DAP) urinary metabolite levels.
Obtained models generally performed poorly at explaining postural control measures. However, when both visual and cognitive conditions were altered-the most challenging balance condition-models for some postural balance measures contained several DAP metabolites and had relatively better fits.
The current results were equivocal regarding associations between postural control measures and DAP metabolite concentrations. However, farmworker status appears to be an important variable in understanding this association. Future work should use a posturally- and cognitively-challenging test condition to reveal any potential associations.
采用数据驱动的方法，探索拉丁裔农场工人和非农场工人的姿势平衡与农药暴露之间的关联。
使用套索正则化广义线性模型，研究在四个实验条件（2 种视觉和 2 种认知难度）下，姿势控制措施与二烷基磷酸酯（DAP）尿代谢物水平之间的关系。
获得的模型通常在解释姿势控制措施方面表现不佳。然而，当视觉和认知条件都改变时——最具挑战性的平衡条件——一些姿势平衡措施的模型包含了几种 DAP 代谢物，并且拟合度相对较好。
目前的结果表明，姿势控制措施与 DAP 代谢物浓度之间存在关联，但结果并不明确。然而，工人身份似乎是理解这种关联的一个重要变量。未来的工作应该使用一种具有挑战性的姿势和认知测试条件来揭示任何潜在的关联。
