Kaiser Permanente Center for Health Research, Portland, OR, USA.
J Occup Environ Med. 2011 Aug;53(8):884-91. doi: 10.1097/JOM.0b013e318222f03a.
Residential proximity to pesticide-treated farmland is an important pesticide exposure pathway.
In-person interviews and biological samples were collected from 100 farmworker and 100 non-farmworker adults and children living in Eastern Washington State. We examined the relationship of residential proximity to farmland to urinary metabolite concentrations of dimethylphosphate (DMTP) and levels of pesticide residues in house dust.
DMTP concentrations were higher in farmworkers than non-farmworkers (71 μg/L vs 6 μg/L) and in farmworker children than non-farmworker children (17 μg/L vs 8 μg/L). Compared to non-farmworker households, farmworker households had higher levels of azinphos-methyl (643 ng/g vs 121 ng/g) and phosmet (153 ng/g vs 50 ng/g). Overall, a 20% reduction in DMTP concentration was observed per mile increase in distance from farmland.
Lower OP metabolite concentrations correlated with increasing distance from farmland.
居住在施用过农药的农田附近是一种重要的农药接触途径。
对居住在华盛顿州东部的 100 名农场工人和 100 名非农场工人及其儿童进行了入户访谈和采集生物样本。我们考察了居住在农田附近与尿代谢物二甲基磷酸酯（DMTP）浓度和室内灰尘中农药残留水平之间的关系。
与非农场工人相比，农场工人的 DMTP 浓度更高（71μg/L 比 6μg/L），农场工人的儿童比非农场工人的儿童更高（17μg/L 比 8μg/L）。与非农场工人家庭相比，农场工人家庭的azinphos-methyl（643ng/g 比 121ng/g）和 phosmet（153ng/g 比 50ng/g）水平更高。总体而言，从农田的距离每增加 1 英里，DMTP 浓度就会降低 20%。
与接触农田的距离增加相关的是 OP 代谢物浓度的降低。
