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伊朗北部尿路感染分离出细菌的患病率及抗生素耐药模式

Prevalence and antibiotic resistance pattern of bacteria isolated from urinary tract infections in Northern Iran.

作者信息

Mihankhah Abbas, Khoshbakht Rahem, Raeisi Mojtaba, Raeisi Vahideh

机构信息

Department of Pathobiology, Faculty of Veterinary Medicine, Amol University of Special Modern Technologies, Amol, Iran.

Cereal Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran.

出版信息

J Res Med Sci. 2017 Sep 26;22:108. doi: 10.4103/jrms.JRMS_889_16. eCollection 2017.

DOI:10.4103/jrms.JRMS_889_16
PMID:29026424
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5629843/
Abstract

BACKGROUND

This study aimed to investigate the bacteria associated with urinary tract infection (UTI) and antibiotic susceptibility pattern of the isolates during 2013-2015 in Northern Iran.

MATERIALS AND METHODS

Overall 3798 patients with clinical symptoms of UTI were subjected as samples, and they were cultured and pure isolated bacteria were identified using biochemical tests and subjected to antibiogram assessment using disc diffusion method.

RESULTS

Totally, 568 (14.96%) from 3798 patients had positive UTI. Four hundred and ninety-seven (87.5%) from 568 isolated bacteria were resistant to at least one antibiotic. , spp., and spp. were the most prevalent bacteria. Isolated bacteria indicated the highest antibiotic resistance to methicillin (76.06%) and ampicillin (89.29%) and also revealed the most sensitivity to imipenem (99.1%) and amikacin (91.57%). Statistical analysis of the resistance pattern trend during 3 years indicated the insignificant increase ( > 0.05) in antibiotic resistance of the isolates.

CONCLUSION

The results of this study revealed a great concern for emerging UTI-related multidrug-resistant strains of bacteria causing UTI in Iran.

摘要

背景

本研究旨在调查2013 - 2015年伊朗北部与尿路感染(UTI)相关的细菌及其分离株的抗生素敏感性模式。

材料与方法

总共3798例有UTI临床症状的患者作为样本,进行培养,使用生化试验鉴定纯分离细菌,并采用纸片扩散法进行药敏评估。

结果

在3798例患者中,共有568例(14.96%)UTI检测呈阳性。568株分离细菌中有497株(87.5%)对至少一种抗生素耐药。 菌属、 菌属和 菌属是最常见的细菌。分离细菌对甲氧西林(76.06%)和氨苄西林(89.29%)的耐药性最高,对亚胺培南(99.1%)和阿米卡星(91.57%)的敏感性最高。对3年期间耐药模式趋势的统计分析表明,分离株的抗生素耐药性无显著增加(>0.

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