Secchin Pedro, Trope Beatriz Moritz, Fernandes Larissa Araujo, Barreiros Glória, Ramos-E-Silva Marcia
Sector of Dermatology and Post-Graduation Course, HUCFF-UFRJ and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Sector of Dermatology and Post-Graduation Course in Dermatology, University Hospital and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Case Rep Dermatol. 2017 Aug 17;9(2):119-129. doi: 10.1159/000471788. eCollection 2017 May-Aug.
Sporotrichosis is the subcutaneous mycosis caused by several species of the Sporothrix genus. With worldwide occurrence, the State of Rio de Janeiro is presently undergoing a zoonotic sporotrichosis epidemic. The form of lymphocutaneous nocardiosis is rare, being caused especially by It appears as a nodular or ulcerated lesion, with multiple painful erythematous nodules or satellite pustules distributed along the lymphatic tract, similar to the lymphocutaneous variant of sporotrichosis. We present a 61-year-old man who, after an insect bite in the left leg, developed an ulcerated lesion associated with ascending lymphangitis, nonresponsive to previous antibiotic therapies. The patient was admitted for investigation, based on the main diagnostic hypothesis of lymphatic cutaneous sporotrichosis entailed by the highly suggestive morphology, associated with the epidemiologic information that he is a resident of the city of Rio de Janeiro. While culture results were being awaited, the patient was medicated with sulfamethoxazole-trimethoprim to cover CA-MRSA and evolved with total healing of the lesions. After hospital discharge, using an ulcer fragment, an sp. was cultivated and was identified by molecular biology. The objective of this report is to demonstrate a case of lymphocutaneous nocardiosis caused by after a probable insect bite. Despite the patient being a resident of the State of Rio de Janeiro (endemic region for sporotrichosis), it is highlighted that it is necessary to be aware of the differential diagnoses of an ulcerated lesion with lymphangitis, favoring an early diagnosis and appropriate treatment of the illness.
孢子丝菌病是由孢子丝菌属的几种菌种引起的皮下真菌病。该病在全球范围内均有发生,里约热内卢州目前正在经历人畜共患孢子丝菌病的流行。皮肤淋巴管型诺卡菌病较为罕见,尤其由……引起。它表现为结节状或溃疡性病变,沿淋巴管分布有多个疼痛性红斑结节或卫星脓疱,类似于孢子丝菌病的皮肤淋巴管型。我们报告一例61岁男性,其左腿被昆虫叮咬后出现溃疡性病变,并伴有上行性淋巴管炎,先前的抗生素治疗无效。基于高度提示性的形态学表现以及患者是里约热内卢市居民的流行病学信息,主要诊断假设为皮肤淋巴管型孢子丝菌病,患者因此入院接受检查。在等待培养结果期间,患者接受了磺胺甲恶唑-甲氧苄啶治疗以覆盖社区获得性耐甲氧西林金黄色葡萄球菌,病变完全愈合。出院后,利用溃疡组织碎片培养出一种……菌,并通过分子生物学鉴定。本报告的目的是展示一例可能因昆虫叮咬后由……引起的皮肤淋巴管型诺卡菌病病例。尽管患者是里约热内卢州(孢子丝菌病的流行地区)的居民,但需要强调的是,必须警惕伴有淋巴管炎的溃疡性病变的鉴别诊断,以便早期诊断和恰当治疗该疾病。