Einer Claudia, Hohenester Simon, Wimmer Ralf, Wottke Lena, Artmann Renate, Schulz Sabine, Gosmann Christian, Simmons Alisha, Leitzinger Christin, Eberhagen Carola, Borchard Sabine, Schmitt Sabine, Hauck Stefanie M, von Toerne Christine, Jastroch Martin, Walheim Ellen, Rust Christian, Gerbes Alexander L, Popper Bastian, Mayr Doris, Schnurr Max, Vollmar Angelika M, Denk Gerald, Zischka Hans
Institute of Molecular Toxicology and Pharmacology, Helmholtz Center Munich, German Research Center for Environmental Health, 85764 Neuherberg, Germany.
Department of Medicine II - Grosshadern, Liver Center Munich, LMU Munich, 81377 Munich, Germany.
Data Brief. 2017 Sep 18;15:163-169. doi: 10.1016/j.dib.2017.09.019. eCollection 2017 Dec.
The data presented in this article describe the fatty acid composition of chow, liver tissue and isolated liver mitochondria from mice fed for 6-24 weeks with a high caloric western diet (WD) in comparison to control diet (normal diet, ND). The fatty acid composition was measured via gas chromatography flame ionization detection (GC-FID). Moreover, WD-induced mitochondrial protein changes are presented in this work and were analyzed by mass spectrometry (LC-MS/MS). For further interpretation and discussion of the presented data please refer to the research article entitled "Mitochondrial adaptation in steatotic mice" (Einer et al., 2017) [1].
本文所呈现的数据描述了用高热量西式饮食（WD）喂养6 - 24周的小鼠的食物、肝脏组织及分离出的肝脏线粒体中的脂肪酸组成，并与对照饮食（正常饮食，ND）进行了比较。脂肪酸组成通过气相色谱火焰离子化检测（GC - FID）进行测定。此外，本研究展示了WD诱导的线粒体蛋白质变化，并通过质谱分析（LC - MS/MS）进行了分析。有关所呈现数据的进一步解读和讨论，请参考题为《脂肪变性小鼠的线粒体适应性》的研究文章（Einer等人，2017年）[1]。
