Okamoto Naoko, Umehara Kaori, Sonoda Junko, Hotta Mitsuyuki, Mizushima Hiroki, Takagi Yutaka, Matsuo Keiko, Baba Naoko
Skin Care Products Research Laboratories, Kao Corporation, Tokyo.
Biological Science Research Laboratories, Kao Corporation, Tochigi.
Clin Cosmet Investig Dermatol. 2017 Oct 3;10:393-401. doi: 10.2147/CCID.S140716. eCollection 2017.
Despite the application of skin care treatments, many infants have skin problems such as dryness and erythema. We proposed a new combination skin care for infants which consisted of a foaming cleanser with lower surfactant activity and moisturizers that contained pseudo-ceramide.
A total of 50 infants (age: 3-24 months) with insignificant levels of dry skin were enrolled in this usage trial. The parents washed the infants with the test cleanser while bathing and then applied the moisturizer (lotion or cream) containing pseudo-ceramide. Prior to and following the 4-week usage period, visual evaluation of the skin condition was conducted by a dermatologist, in addition to instrumental analysis.
Erythema and papule, accompanied by dryness, were commonly observed at week 0. However, by week 4, these symptoms significantly improved; the condition of none of the subjects deteriorated. The number of infants with lower cutaneous barrier function and higher skin pH decreased. The parents of the infants recognized improvements in the skin symptoms and were appreciative of the test materials.
The combined usage of the foaming cleanser with lower surfactant activity and a moisturizer containing pseudo-ceramide may be effective in maintaining healthy infant skin and ameliorating the skin symptoms.
尽管应用了皮肤护理疗法,但许多婴儿仍有皮肤问题,如干燥和红斑。我们提出了一种新的婴儿联合皮肤护理方法,该方法包括一种表面活性剂活性较低的泡沫洁面产品和含有假神经酰胺的保湿剂。
本使用试验共纳入50名干性皮肤程度不严重的婴儿(年龄:3至24个月)。家长在给婴儿洗澡时用试验洁面产品为其清洗,然后涂抹含有假神经酰胺的保湿剂(乳液或乳霜)。在4周使用期前后,除了仪器分析外,皮肤科医生还对皮肤状况进行了视觉评估。
在第0周时,常见伴有干燥的红斑和丘疹。然而,到第4周时,这些症状明显改善;没有受试者的情况恶化。皮肤屏障功能较低且皮肤pH值较高的婴儿数量减少。婴儿的家长认识到皮肤症状有所改善,并对试验产品表示满意。
联合使用表面活性剂活性较低的泡沫洁面产品和含有假神经酰胺的保湿剂可能有助于维持婴儿皮肤健康并改善皮肤症状。