School of Semiconductor and Chemical Engineering, Nanomaterials Processing Research Center, Chonbuk National University, 567 Baekjedaero, Deokjin-gu, Jeonju-si, Jeollabuk-do 54896, Republic of Korea.
School of Semiconductor and Chemical Engineering, Nanomaterials Processing Research Center, Chonbuk National University, 567 Baekjedaero, Deokjin-gu, Jeonju-si, Jeollabuk-do 54896, Republic of Korea.
J Colloid Interface Sci. 2018 Feb 15;512:21-28. doi: 10.1016/j.jcis.2017.10.037. Epub 2017 Oct 12.
Herein, we fabricated nonenzymatic flexible field-effect transistor (f-FET) based glucose sensor using nickel oxide quantum dots (NiO QDs) modified zinc oxide nanorods (ZnO NRs). The ZnO NRs surfaces were coated with NiO QDs using radio frequency (RF) magnetron sputtering to enhance the electrocatalytic feature and the surface area of ZnO NRs. Under physiological conditions (pH 7.4), the nonenzymatic f-FET glucose sensor shows two linear ranges of 0.001-10mM and 10-50mM with the high sensitivity of 13.14μAcmmM and 7.31μAcmmM, respectively, along with good selectivity, stability and repeatability during glucose detection. The examination of human whole blood and serum samples reveal that the nonenzymatic f-FET based glucose sensor is capable of measuring glucose concentration efficiently in the presence of interfering species and thus can be offered as a promising device for further applications in clinical and non-clinical fields.
在这里，我们使用氧化镍量子点 (NiO QDs) 修饰氧化锌纳米棒 (ZnO NRs) 制造了基于非酶柔性场效应晶体管 (f-FET) 的葡萄糖传感器。通过射频 (RF) 磁控溅射在 ZnO NRs 表面涂覆 NiO QDs，以增强 ZnO NRs 的电催化性能和表面积。在生理条件 (pH 7.4) 下，非酶 f-FET 葡萄糖传感器在 0.001-10mM 和 10-50mM 两个线性范围内具有高灵敏度，分别为 13.14μAcmmM 和 7.31μAcmmM，同时在葡萄糖检测过程中具有良好的选择性、稳定性和可重复性。对人全血和血清样本的检测表明，基于非酶 f-FET 的葡萄糖传感器能够在存在干扰物质的情况下有效地测量葡萄糖浓度，因此有望成为临床和非临床领域进一步应用的有前途的设备。
