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用于精确检测血糖水平的纳米生物传感器的最新进展。

Recent Progress in Nanobiosensors for Precise Detection of Blood Glucose Level.

作者信息

Khosravi Ardakani Haniye, Gerami Mitra, Chashmpoosh Mostafa, Omidifar Navid, Gholami Ahmad

机构信息

Biotechnology Research Center, University of Medical Sciences, Shiraz, Iran.

Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Biochem Res Int. 2022 Jan 17;2022:2964705. doi: 10.1155/2022/2964705. eCollection 2022.

DOI:10.1155/2022/2964705
PMID:35083086
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8786499/
Abstract

Diabetes mellitus (DM) follows a series of metabolic diseases categorized by high blood sugar levels. Owing to the increasing diabetes disease in the world, early diagnosis of this disease is critical. New methods such as nanotechnology have made significant progress in many areas of medical science and physiology. Nanobiosensors are very sensible and can identify single virus particles or even low concentrations of a material that can be inherently harmful. One of the main factors for developing glucose sensors in the body is the diagnosis of hypoglycemia in individuals with insulin-dependent diabetes. Therefore, this study aimed to evaluate the most up-to-date and fastest glucose detection method by nanosensors and, as a result, faster and better treatment in medical sciences. In this review, we try to explore new ways to control blood glucose levels and treat diabetes. We begin with a definition of biosensors and their classification and basis, and then we examine the latest biosensors in glucose detection and new biosensors applications, including the artificial pancreas and updating quantum graphene data.

摘要

糖尿病(DM)是一系列以高血糖水平为特征的代谢性疾病。由于全球糖尿病发病率不断上升,该疾病的早期诊断至关重要。纳米技术等新方法在医学和生理学的许多领域都取得了重大进展。纳米生物传感器非常灵敏,能够识别单个病毒颗粒,甚至能够检测出低浓度的潜在有害物质。在体内开发葡萄糖传感器的一个主要因素是诊断胰岛素依赖型糖尿病患者的低血糖症。因此,本研究旨在评估纳米传感器最先进、最快速的葡萄糖检测方法,从而在医学上实现更快、更好的治疗。在这篇综述中,我们试图探索控制血糖水平和治疗糖尿病的新方法。我们首先对生物传感器进行定义,并介绍其分类和原理,然后研究葡萄糖检测中的最新生物传感器以及新型生物传感器的应用,包括人工胰腺和量子石墨烯数据的更新。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71be/8786499/fcbf5d07a74a/bri2022-2964705.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71be/8786499/0ed0df2528af/bri2022-2964705.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71be/8786499/5ef3b1c63399/bri2022-2964705.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71be/8786499/fcbf5d07a74a/bri2022-2964705.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71be/8786499/0ed0df2528af/bri2022-2964705.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71be/8786499/5ef3b1c63399/bri2022-2964705.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71be/8786499/fcbf5d07a74a/bri2022-2964705.003.jpg

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