Rana Shiwangi, Mendiratta Vibhu, Chander Ram
Department of Dermatology, Lady Hardinge Medical College, New Delhi, India.
J Cosmet Dermatol. 2017 Dec;16(4):454-459. doi: 10.1111/jocd.12377. Epub 2017 Oct 26.
Microneedling with dermaroller and glycolic acid peels is commonly used for treatment of acne scars.
To compare efficacy of microneedling alone versus combination of microneedling with serial 70% glycolic acid peel in management of atrophic acne scars.
METHODS & MATERIALS: Sixty patients with atrophic acne scars were randomized into group 1 receiving microneedling at 0, 6, and 12 weeks and group 2 receiving microneedling at 0, 6, and 12 weeks along with 70% glycolic acid peel at 3, 9, and 15 weeks. Acne scar scoring was performed by a blinded observer using ECCA (Echelle d'evaluation clinique des cicatrices d'acne) scoring at baseline and after 22 weeks. Additionally, patients were asked to grade the improvement in acne scars and skin texture on visual analogue scale (VAS).
Of 60 patients, 52 completed the 22-week study period. The decrement from baseline in mean ECCA score was more in group 2 as compared to group 1 (39.65±2.50 vs 29.58±0.18; P<.001). Group 2 also showed more improvement in skin texture as compared to group 1 on VAS.
Addition of sequential 70% glycolic acid peel to microneedling gives better scar improvement as compared to microneedling alone. In addition to this, it also improves skin texture.
微针滚轮联合乙醇酸焕肤常用于治疗痤疮瘢痕。
比较单纯微针治疗与微针联合70%乙醇酸系列焕肤治疗萎缩性痤疮瘢痕的疗效。
60例萎缩性痤疮瘢痕患者被随机分为两组，第1组在第0、6和12周接受微针治疗，第2组在第0、6和12周接受微针治疗，并在第3、9和15周接受70%乙醇酸焕肤。在基线和22周后，由一名盲法观察者使用ECCA（痤疮瘢痕临床评估量表）对痤疮瘢痕进行评分。此外，要求患者在视觉模拟量表（VAS）上对痤疮瘢痕和皮肤质地的改善程度进行评分。
60例患者中，52例完成了22周的研究期。与第1组相比，第2组的平均ECCA评分从基线的下降幅度更大（39.65±2.50对29.58±0.18；P<0.001）。在VAS上，第2组的皮肤质地改善也比第1组更明显。
与单纯微针治疗相比，微针联合70%乙醇酸系列焕肤能更好地改善瘢痕。除此之外，它还能改善皮肤质地。
