抑郁症患者血小板中色氨酸的积累。
Tryptophan accumulation by blood platelets of depressed patients.
作者信息
Wood K, Swade C, Coppen A
出版信息
J Neural Transm Suppl. 1979(15):161-3. doi: 10.1007/978-3-7091-2243-3_14.
PMID:290754
Abstract
The accumulation of tryptophan by blood platelets has been investigated in depressive patients and controls using short incubation times and low substrate concentrations. The accumulation of tryptophan by the platelet is significantly greater in the acutely depressed patients than the control group. The results are discussed with reference to tryptophan transport in depression and also to the regulation of plasma levels of tryptophan.
摘要
利用短孵育时间和低底物浓度，对抑郁症患者和对照组血小板中色氨酸的积累情况进行了研究。急性抑郁症患者血小板中色氨酸的积累显著高于对照组。结合抑郁症中色氨酸的转运以及血浆色氨酸水平的调节对结果进行了讨论。
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