Pellegrini Andrea, Tacci Fabrizio, Leigheb Massimiliano, Costantino Cosimo, Pedrazzini Alessio, Pedrazzi Giuseppe, Vaienti Enrico, Ceccarelli Francesco, Pogliacomi Francesco
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Acta Biomed. 2017 Oct 18;88(4S):43-49. doi: 10.23750/abm.v88i4-S.6793.
In a context of bone fragility, primitive and subsequent fractures are a growing problem in the industrialized countries where the mean age of the population is constantly increasing. Among the various factors that favor a fragility fracture, the most important is osteoporosis, a pathology that can be prevented through diagnostic screenings and treated by pharmacological and rehabilitative therapies. The aim of this study is to identify the subjects who are likely to have a higher risk of subsequent fractures of the trochanteric region through a retrospective radiographic evaluation of patients affected by low-energy trochanteric fractures and operated by intramedullary fixation between June 2013 and June 2015, so they can be targeted for prevention interventions.
Three hundred and sixty-one patients yet alive were analyzed 2 years after surgery. Fifty-one (group 1), characterized by another contralateral trochanteric femoral fracture, were included. All subjects were retrospectively examined with the analysis of contralateral femur X-ray performed at the time of initial trauma in order to detect a condition of bone fragility and a predisposition to fractures by evaluating three radiographic indices (Singh index, Dorr's classification and Cortical Thickness Index). Patients of group 1 were compared to the other 310 patients (group 2) affected by isolated trochanteric fracture.
Group 1 had all radiographic indices worse than group 2.
The results observed suggest that orthopedists can use radiographic indices, in particular Cortical Thickness Index, as a valuable, simple and inexpensive screening tool for prevention of recurrent osteoporotic fractures.
在骨脆性的背景下,原发性骨折及后续骨折在工业化国家正成为一个日益严重的问题,这些国家的人口平均年龄在持续增长。在导致脆性骨折的各种因素中,最重要的是骨质疏松症,这是一种可通过诊断性筛查预防,并通过药物和康复治疗进行治疗的疾病。本研究的目的是通过对2013年6月至2015年6月期间因低能量转子间骨折接受髓内固定手术的患者进行回顾性影像学评估,确定那些转子间区域后续骨折风险可能更高的受试者,以便对他们进行预防干预。
对术后2年仍存活的361例患者进行分析。纳入51例(第1组),其特征为对侧股骨转子间骨折。对所有受试者进行回顾性检查,分析初次创伤时对侧股骨的X线片,通过评估三个影像学指标(辛格指数、多尔分类和皮质厚度指数)来检测骨脆性状况和骨折易感性。将第1组患者与其他310例单纯转子间骨折患者(第2组)进行比较。
第1组的所有影像学指标均比第2组差。
观察结果表明,骨科医生可将影像学指标,特别是皮质厚度指数,作为一种有价值、简单且廉价的预防复发性骨质疏松性骨折的筛查工具。