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Targeting in Cancer Therapies.

作者信息

Mangues Ramon, Vázquez Esther, Villaverde Antonio

机构信息

Biomedical Research Institute Sant Pau (IIB-SantPau) and Josep Carreras Leukemia Research Institute, Hospital de la Santa Creu i Sant Pau, 08025 Barcelona, Spain.

CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Bellaterra, 08193 Cerdanyola del Vallès, Spain.

出版信息

Med Sci (Basel). 2016 Mar 8;4(1):6. doi: 10.3390/medsci4010006.

DOI:10.3390/medsci4010006
PMID:29083369
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5635766/
Abstract

Drug developers recruit and combine principles, procedures and strategies from chemistry, pharmacology, nanotechnology and biotechnology, focusing on the generation of functional vehicles as nano-carriers of drugs for improved stability and enhanced intracellular delivery.[...].

摘要

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本文引用的文献

1
Recombinant pharmaceuticals from microbial cells: a 2015 update.来自微生物细胞的重组药物:2015年最新进展
Microb Cell Fact. 2016 Feb 9;15:33. doi: 10.1186/s12934-016-0437-3.
2
Cancer nanotherapeutics in clinical trials.处于临床试验阶段的癌症纳米疗法。
Cancer Treat Res. 2015;166:293-322. doi: 10.1007/978-3-319-16555-4_13.
3
Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery.多功能、刺激响应型纳米颗粒给药系统。
Nat Rev Drug Discov. 2014 Nov;13(11):813-27. doi: 10.1038/nrd4333. Epub 2014 Oct 7.
4
Antibody-drug conjugates in cancer therapy.抗体药物偶联物在癌症治疗中的应用。
Annu Rev Med. 2013;64:15-29. doi: 10.1146/annurev-med-050311-201823. Epub 2012 Oct 3.
5
The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma.本妥昔单抗维迪昔单抗在复发型霍奇金淋巴瘤和系统性间变性大细胞淋巴瘤中的发现和发展。
Nat Biotechnol. 2012 Jul 10;30(7):631-7. doi: 10.1038/nbt.2289.
6
The journey of a drug-carrier in the body: an anatomo-physiological perspective.药物载体在体内的旅程:解剖生理学视角。
J Control Release. 2012 Jul 20;161(2):152-63. doi: 10.1016/j.jconrel.2011.09.098. Epub 2011 Oct 6.
7
Nanomedicine(s) under the microscope.纳米医学在显微镜下。
Mol Pharm. 2011 Dec 5;8(6):2101-41. doi: 10.1021/mp200394t. Epub 2011 Oct 26.
8
Strategies in the design of nanoparticles for therapeutic applications.用于治疗应用的纳米粒子设计策略。
Nat Rev Drug Discov. 2010 Aug;9(8):615-27. doi: 10.1038/nrd2591. Epub 2010 Jul 9.
9
Pharmacokinetic variability of anticancer agents.抗癌药物的药代动力学变异性。
Nat Rev Cancer. 2005 Jun;5(6):447-58. doi: 10.1038/nrc1629.