Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, 430079, PR China.
Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, 430079, PR China.
Anal Chim Acta. 2018 Oct 31;1029:97-103. doi: 10.1016/j.aca.2018.04.048. Epub 2018 Apr 21.
In this paper, a new colorimetric and ratiometric fluorescent probe for the rapid detection of phosgene is reported. This probe is based on a readily prepared and highly fluorescent iminocoumarin, which reacts rapidly with phosgene to form a cyclic carbamate product to produce, distinctive colorimetric and ratiometric fluorescent signal changes. The detection of phosgene with this probe is fast (complete within 2 min), highly selective and sensitive with a detection limit of 27 nM in solution. Moreover, this probe can be used to prepare easy-to-use paper test strips for convenient visual and fluorescent detection of phosgene gas even at a concentration of 0.1 mg/L. Overall, this work provides a very promising dual colorimetric and ratiometric fluorescent probe for rapid and sensitive detection of phosgene both in solution and in the gas phase.
本文报道了一种用于快速检测光气的新型比色和比率荧光探针。该探针基于一种易于制备且具有高荧光性的亚胺-香豆素，它能与光气快速反应，形成环状氨基甲酸酯产物，产生明显的比色和比率荧光信号变化。该探针对光气的检测速度快（在 2 分钟内完成），具有高度选择性和灵敏度，在溶液中的检测限为 27nM。此外，该探针还可用于制备易于使用的纸质测试条，即使在 0.1mg/L 的浓度下，也可方便地进行光气气体的可视化和荧光检测。总的来说，这项工作为快速、灵敏地检测溶液和气相中的光气提供了一种非常有前景的双比色和比率荧光探针。
