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不同年龄段代谢综合征的性别差异及其与饮食多样性的关联。

Gender difference of metabolic syndrome and its association with dietary diversity at different ages.

作者信息

Tian Xu, Xu Xiaohui, Zhang Kai, Wang Hui

机构信息

College of Economics and Management, China Center for Food Security Studies, Nanjing Agricultural University, Nanjing, Jiangsu, China.

Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China.

出版信息

Oncotarget. 2017 Sep 2;8(43):73568-73578. doi: 10.18632/oncotarget.20625. eCollection 2017 Sep 26.

DOI:10.18632/oncotarget.20625
PMID:29088727
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5650282/
Abstract

BACKGROUND

Previous research indicated that dietary diversity had favorable association with metabolic syndrome (MetS), and it has not been investigated in China.

METHODS

Adults (aged 18+) with complete dietary and biochemical data were collected from 2009 China Health and Nutrition Survey (=4308). Dietary diversity was measured by modified Dietary Diversity Score (DDS). MetS was defined by the harmonized criteria. The association between DDS and MetS was investigated by multivariable adjusted logistic regression.

RESULTS

An inverse-U shape relationship between MetS risk and age was detected for both genders, and female were more vulnerable than male at old times. More diversified diet decreased the risk of MetS for young female (≥18 & ≤45), similar trends were detected in serum TGs, abdominal adiposity, blood pressure, and fasting blood glucose (all <0.05). However, this association reversed for old female (>60) and male adults (>45&≤60). Greater DDS was associated with higher serum TGs, and lower HDL-C level for male adults, higher blood pressure for old men, but lower blood pressure and fasting blood glucose in young men (all <0.05).

CONCLUSION

Male adults and old female had the highest risk of getting MetS. More diversified diet decreased MetS risk for young female, but increased the risk for male adults and old female.

摘要

背景

先前的研究表明饮食多样性与代谢综合征(MetS)存在有益关联,而在中国尚未对此进行研究。

方法

从2009年中国健康与营养调查中收集了具有完整饮食和生化数据的成年人(年龄≥18岁)(n = 4308)。饮食多样性通过改良的饮食多样性评分(DDS)来衡量。MetS根据统一标准进行定义。通过多变量调整逻辑回归研究DDS与MetS之间的关联。

结果

检测到男女MetS风险与年龄之间均呈倒U形关系,且老年女性比老年男性更易患MetS。饮食更多样化可降低年轻女性(≥18岁且≤45岁)患MetS的风险,血清甘油三酯、腹部肥胖、血压和空腹血糖也呈现类似趋势(均P<0.05)。然而,老年女性(>60岁)和成年男性(>45岁且≤60岁)的这种关联则相反。较高的DDS与成年男性较高的血清甘油三酯和较低的高密度脂蛋白胆固醇水平相关,与老年男性较高的血压相关,但与年轻男性较低的血压和空腹血糖相关(均P<0.05)。

结论

成年男性和老年女性患MetS的风险最高。饮食更多样化可降低年轻女性患MetS的风险,但会增加成年男性和老年女性的患病风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fd5/5650282/e5959bc626a5/oncotarget-08-73568-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fd5/5650282/ff508660e448/oncotarget-08-73568-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fd5/5650282/e5959bc626a5/oncotarget-08-73568-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fd5/5650282/ff508660e448/oncotarget-08-73568-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fd5/5650282/e5959bc626a5/oncotarget-08-73568-g002.jpg

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