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慢性心力衰竭患者爬楼梯时摄氧量和通气的反应。

Response in oxygen uptake and ventilation during stair climbing in patients with chronic heart failure.

作者信息

Reddy H K, McElroy P A, Janicki J S, Weber K T

机构信息

Division of Cardiology, Michael Reese Hospital, University of Chicago Pritzker School of Medicine, Illinois 60616.

出版信息

Am J Cardiol. 1989 Jan 15;63(3):222-5. doi: 10.1016/0002-9149(89)90289-0.

Abstract

To examine the level of muscular work and ventilatory response to stair climbing (mobile Stairmaster staircase, 1 step/2.5 s), respiratory gas exchange, ventilation, heart rate and arterial pressure were monitored in patients with chronic heart failure and their response compared with that of normal individuals. Aerobic capacity (maximal oxygen uptake) and anaerobic threshold during treadmill exercise were also determined and used to ascertain the metabolic cost of stair climbing. No differences were observed in the response of mean arterial blood pressure between the 12 patients and 10 normal subjects during exercise or recovery. However, the heart rate and oxygen consumption obtained during exercise were significantly lower in the patients with chronic heart failure than in the normal subjects (p less than 0.05). All patients with a maximal oxygen uptake less than 20 ml/min/kg during treadmill exercise had an oxygen uptake during stair climbing that exceeded their anaerobic threshold and, consequently, they attained a significantly (p less than 0.01) higher level of ventilation during exercise and recovery. This was not the case for those patients with greater aerobic capacity. Therefore, it is concluded that stair climbing for the 12 patients with heart failure and moderate to moderately severe impairment in aerobic capacity represents strenuous anaerobic exercise. The resultant excess ventilation may explain the limiting sensation of dyspnea that is frequently experienced by these patients during and after stair climbing.

摘要

为了检测慢性心力衰竭患者爬楼梯(移动的斯泰迈斯特楼梯,每2.5秒1步)时的肌肉工作水平和通气反应,监测了呼吸气体交换、通气、心率和动脉压,并将他们的反应与正常个体进行比较。还测定了跑步机运动期间的有氧能力(最大摄氧量)和无氧阈值,以确定爬楼梯的代谢成本。在运动或恢复过程中,12例患者和10名正常受试者的平均动脉血压反应未观察到差异。然而,慢性心力衰竭患者运动期间的心率和耗氧量显著低于正常受试者(p<0.05)。在跑步机运动期间最大摄氧量低于20 ml/min/kg的所有患者,爬楼梯时的耗氧量超过了他们的无氧阈值,因此,他们在运动和恢复期间的通气水平显著更高(p<0.01)。有氧能力较强的患者则并非如此。因此,得出结论,对于12例心力衰竭且有氧能力有中度至中度严重损害的患者,爬楼梯代表剧烈的无氧运动。由此产生的过度通气可能解释了这些患者在爬楼梯期间及之后经常体验到的呼吸困难的受限感觉。

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