Beijing Key Laboratory of Clinical Epidemiology, School of Public Health, Capital Medical University, Beijing, 100069, China.
Department of Cardiology, Tangshan People's Hospital, North China University of Science and Technology, Tangshan, 063000, China.
Sci Rep. 2017 Nov 3;7(1):14975. doi: 10.1038/s41598-017-15101-5.
Suboptimal health status (SHS) is a physical state between health and illness, and previous studies suggested that SHS is associated with majority components of cardiovascular health metrics defined by American Heart Association (AHA). We investigated the association between SHS and cardiovascular health metrics in a cross-sectional analysis of China suboptimal health cohort study (COACS) consisting of 4313 participants (60.30% women) aged from 18 to 65 years old. The respective prevalence of SHS is 7.10%, 9.18%, 10.04% and 10.62% in the first, second, third and fourth quartiles of ideal cardiovascular health (CVH) metrics (P for trend = 0.012). Participants in the largest quartile of ideal CVH metrics show a lower likelihood of having optimal SHS score compared to those in the smallest quartile (odds ratio (OR), 0.43; 95% confidence interval (CI), 0.32-0.59), after adjusting for age, gender, marital status, alcohol consumption, income level and education. Four metrics (smoking, physical inactivity, poor dietary intake and ideal control of blood pressure are significantly correlated with the risk of SHS. The present study suggests that ideal CVH metrics are associated with a lower prevalence of SHS, and the combined evaluation of SHS and CVH metrics allows the risk classification of cardiovascular disease, and thus consequently contributes to the prevention of cardiovascular diseases.
亚健康状态（SHS）是一种介于健康和疾病之间的身体状态，先前的研究表明，SHS 与美国心脏协会（AHA）定义的大多数心血管健康指标成分有关。我们在中国亚健康队列研究（COACS）的横断面分析中研究了 SHS 与心血管健康指标之间的关系，该研究包括 4313 名年龄在 18 至 65 岁之间的参与者（女性占 60.30%）。在理想心血管健康（CVH）指标的第一、二、三和四分位数中，SHS 的分别患病率为 7.10%、9.18%、10.04%和 10.62%（趋势 P=0.012）。与最小四分位数相比，最大四分位数的理想 CVH 指标参与者具有较低的最佳 SHS 评分可能性（比值比（OR），0.43；95%置信区间（CI），0.32-0.59），调整年龄、性别、婚姻状况、饮酒、收入水平和教育程度后。四项指标（吸烟、身体活动不足、不良饮食摄入和理想血压控制）与 SHS 风险显著相关。本研究表明，理想的 CVH 指标与 SHS 的低患病率相关，SHS 和 CVH 指标的综合评估可以对心血管疾病的风险进行分类，从而有助于预防心血管疾病。
