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使用富含萜类化合物的罗勒叶提取物合成的银纳米颗粒的抗氧化、抗菌和细胞毒性潜力。

Antioxidant, antibacterial and cytotoxic potential of silver nanoparticles synthesized using terpenes rich extract of L. leaves.

作者信息

P Patil Shriniwas, T Kumbhar Subhash

机构信息

Department of Pharmacognosy, SCES's Indira College of Pharmacy, Pune, India.

Department of Pharmacology, SCES's Indira College of Pharmacy, Pune, India.

出版信息

Biochem Biophys Rep. 2017 Mar 10;10:76-81. doi: 10.1016/j.bbrep.2017.03.002. eCollection 2017 Jul.

DOI:10.1016/j.bbrep.2017.03.002
PMID:29114571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5637243/
Abstract

Several attempts have been made for green synthesis of silver nanoparticles (AgNPs) using different plant extracts. Present study revealed that, antioxidant, antibacterial and cytotoxic AgNPs were synthesized using terpenes-rich extract (TRE) of environmentally notorious Lantana camara L. leaves. AgNPs were characterized by advanced techniques like UV-Visible and Infra red spectroscopy; XRD, SEM techniques as terpenes coated sphere shaped NPs with average diameter 425 nm. Further, on evaluation, AgNPs were found to exhibit dose - dependent antioxidant potential, good to moderate antibacterial activity against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa; and toxicity on Brine shrimp (A. salinanauplii) with LD value 514.50 µg/ml.

摘要

人们已经进行了多次尝试，使用不同的植物提取物来绿色合成银纳米颗粒（AgNPs）。目前的研究表明，利用环境中臭名昭著的马缨丹叶片富含萜类的提取物（TRE）合成了具有抗氧化、抗菌和细胞毒性的AgNPs。通过紫外可见光谱和红外光谱等先进技术对AgNPs进行了表征；XRD、SEM技术显示其为萜类包裹的球形纳米颗粒，平均直径为425纳米。此外，经评估发现，AgNPs表现出剂量依赖性的抗氧化潜力，对金黄色葡萄球菌、大肠杆菌和铜绿假单胞菌具有良好至中等的抗菌活性；对卤虫（Artemia salina nauplii）具有毒性，LD值为514.50微克/毫升。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/3eace3752ff1/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/7613fcb52105/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/cc5ad18a47b1/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/b553fcae1028/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/ff2922abba78/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/39dd729d6425/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/5202bfbdd207/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/3eace3752ff1/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/7613fcb52105/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/cc5ad18a47b1/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/b553fcae1028/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/ff2922abba78/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/39dd729d6425/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/5202bfbdd207/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/3eace3752ff1/gr6.jpg

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