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使用富含萜类化合物的罗勒叶提取物合成的银纳米颗粒的抗氧化、抗菌和细胞毒性潜力。

Antioxidant, antibacterial and cytotoxic potential of silver nanoparticles synthesized using terpenes rich extract of L. leaves.

作者信息

P Patil Shriniwas, T Kumbhar Subhash

机构信息

Department of Pharmacognosy, SCES's Indira College of Pharmacy, Pune, India.

Department of Pharmacology, SCES's Indira College of Pharmacy, Pune, India.

出版信息

Biochem Biophys Rep. 2017 Mar 10;10:76-81. doi: 10.1016/j.bbrep.2017.03.002. eCollection 2017 Jul.

Abstract

Several attempts have been made for green synthesis of silver nanoparticles (AgNPs) using different plant extracts. Present study revealed that, antioxidant, antibacterial and cytotoxic AgNPs were synthesized using terpenes-rich extract (TRE) of environmentally notorious Lantana camara L. leaves. AgNPs were characterized by advanced techniques like UV-Visible and Infra red spectroscopy; XRD, SEM techniques as terpenes coated sphere shaped NPs with average diameter 425 nm. Further, on evaluation, AgNPs were found to exhibit dose - dependent antioxidant potential, good to moderate antibacterial activity against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa; and toxicity on Brine shrimp (A. salinanauplii) with LD value 514.50 µg/ml.

摘要

人们已经进行了多次尝试,使用不同的植物提取物来绿色合成银纳米颗粒(AgNPs)。目前的研究表明,利用环境中臭名昭著的马缨丹叶片富含萜类的提取物(TRE)合成了具有抗氧化、抗菌和细胞毒性的AgNPs。通过紫外可见光谱和红外光谱等先进技术对AgNPs进行了表征;XRD、SEM技术显示其为萜类包裹的球形纳米颗粒,平均直径为425纳米。此外,经评估发现,AgNPs表现出剂量依赖性的抗氧化潜力,对金黄色葡萄球菌、大肠杆菌和铜绿假单胞菌具有良好至中等的抗菌活性;对卤虫(Artemia salina nauplii)具有毒性,LD值为514.50微克/毫升。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d655/5637243/7613fcb52105/fx1.jpg

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