Samanta Supravat, Ravi Chitrakar, Rao Sadu Nageswara, Joshi Abhisek, Adimurthy Subbarayappa
Academy of Scientific & Innovative Research, CSIR-Central Salt & Marine Chemicals Research Institute, G.B. Marg, Bhavnagar-364 002, Gujarat, India.
Org Biomol Chem. 2017 Nov 22;15(45):9590-9594. doi: 10.1039/c7ob02504a.
The regioselective C-H amination of quinoline amides (C5) and imidazopyridines (C3) under transition-metal-free conditions at room temperature with a high degree of functional group tolerance is reported. The C-H amination promoted by visible light in the presence of a photocatalyst with a wide range of heteroamines makes the present protocol more sustainable.
据报道，喹啉酰胺（C5）和咪唑并吡啶（C3）在无过渡金属条件下于室温进行区域选择性C-H胺化反应，具有高度的官能团耐受性。在光催化剂存在下，可见光促进的C-H胺化反应与多种杂环胺发生反应，使得本方法更具可持续性。
