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Predictable response: Finding optimal drugs and doses using artificial intelligence.

作者信息

Chakradhar Shraddha

出版信息

Nat Med. 2017 Nov 7;23(11):1244-1247. doi: 10.1038/nm1117-1244.

DOI:10.1038/nm1117-1244
PMID:29117178
Abstract
摘要

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1
Predictable response: Finding optimal drugs and doses using artificial intelligence.可预测反应：利用人工智能寻找最佳药物和剂量。
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Therapeutic drug monitoring for mycophenolic acid is value for (little) money.霉酚酸的治疗药物监测性价比（很低）。
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[Preventing rejection, minimizing toxicity: optimized therapy with cyclosporin].预防排斥反应，降低毒性：环孢素的优化治疗
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Pharmacokinetics of rapamycin.
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[Combination of cyclosporin and ketoconazole in immunosuppression schemes in patients with transplanted kidney].肾移植患者免疫抑制方案中环孢素与酮康唑的联合应用
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J Heart Lung Transplant. 1995 Nov-Dec;14(6 Pt 1):1162-72.
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Neoral cyclosporine.
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Modeling new immunoregulatory therapeutics as antimicrobial alternatives for treating Clostridium difficile infection.将新型免疫调节疗法作为治疗艰难梭菌感染的抗菌替代方案进行建模。
Artif Intell Med. 2017 May;78:1-13. doi: 10.1016/j.artmed.2017.05.003. Epub 2017 May 9.
2
Machine Learning and Prediction in Medicine - Beyond the Peak of Inflated Expectations.医学中的机器学习与预测——超越过高期望的顶峰
N Engl J Med. 2017 Jun 29;376(26):2507-2509. doi: 10.1056/NEJMp1702071.
3
Identification of adverse drug-drug interactions through causal association rule discovery from spontaneous adverse event reports.
基于人工智能的现代教育技术在数字背景下的视觉解析。
Comput Intell Neurosci. 2022 Sep 23;2022:1924138. doi: 10.1155/2022/1924138. eCollection 2022.
4
Motive perception pathways to the release of personal information to healthcare organizations.向医疗机构披露个人信息的动机感知途径。
BMC Med Inform Decis Mak. 2022 Sep 13;22(1):240. doi: 10.1186/s12911-022-01986-4.
5
Relationship between Artificial Intelligence-Based General Anesthetics and Postoperative Cognitive Dysfunction.基于人工智能的全身麻醉与术后认知功能障碍的关系。
J Healthc Eng. 2021 Apr 1;2021:5553029. doi: 10.1155/2021/5553029. eCollection 2021.
6
The role of artificial intelligence in healthcare: a structured literature review.人工智能在医疗保健中的作用：一项结构化文献综述。
BMC Med Inform Decis Mak. 2021 Apr 10;21(1):125. doi: 10.1186/s12911-021-01488-9.
7
Smart diagnostics devices through artificial intelligence and mechanobiological approaches.通过人工智能和机械生物学方法实现的智能诊断设备。
3 Biotech. 2020 Aug;10(8):351. doi: 10.1007/s13205-020-02342-x. Epub 2020 Jul 22.
8
Enabling Technologies for Personalized and Precision Medicine.个性化与精准医学的使能技术
Trends Biotechnol. 2020 May;38(5):497-518. doi: 10.1016/j.tibtech.2019.12.021. Epub 2020 Jan 21.
9
High-performance medicine: the convergence of human and artificial intelligence.高性能医学：人机智能融合。
Nat Med. 2019 Jan;25(1):44-56. doi: 10.1038/s41591-018-0300-7. Epub 2019 Jan 7.
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Challenges in Personalized Nutrition and Health.个性化营养与健康面临的挑战。
Front Nutr. 2018 Nov 29;5:117. doi: 10.3389/fnut.2018.00117. eCollection 2018.
通过从自发不良事件报告中发现因果关联规则来识别药物-药物不良相互作用。
Artif Intell Med. 2017 Feb;76:7-15. doi: 10.1016/j.artmed.2017.01.004. Epub 2017 Feb 10.
4
A data-driven approach for evaluating multi-modal therapy in traumatic brain injury.一种基于数据驱动的方法，用于评估创伤性脑损伤的多模式治疗。
Sci Rep. 2017 Feb 16;7:42474. doi: 10.1038/srep42474.
5
Individualizing liver transplant immunosuppression using a phenotypic personalized medicine platform.采用表型个体化医学平台实现肝移植免疫抑制的个体化。
Sci Transl Med. 2016 Apr 6;8(333):333ra49. doi: 10.1126/scitranslmed.aac5954.
6
"The Patient Is Dying, Please Call the Chaplain": The Activities of Chaplains in One Medical Center's Intensive Care Units.“患者生命垂危，请呼叫牧师”：某医疗中心重症监护病房牧师的工作
J Pain Symptom Manage. 2015 Oct;50(4):501-6. doi: 10.1016/j.jpainsymman.2015.05.003. Epub 2015 May 27.
7
Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm.使用随机搜索算法引导的组合药物对细胞功能进行闭环控制。
Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5105-10. doi: 10.1073/pnas.0800823105. Epub 2008 Mar 20.