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用于体弱和老年人群膀胱出口梗阻的热膨胀前列腺支架:未充分利用的程序?

Thermo-expandable prostatic stents for bladder outlet obstruction in the frail and elderly population: An underutilized procedure?

机构信息

Department of Urology, Ballarat Health Services, Ballarat, Australia.

St. John of God Hospital Ballarat, Ballarat, Australia.

出版信息

Investig Clin Urol. 2017 Nov;58(6):447-452. doi: 10.4111/icu.2017.58.6.447. Epub 2017 Oct 23.

Abstract

PURPOSE

To report our outcomes with the use of a thermo-expandable metallic intraprostatic stent (Memokath) for patients with bladder outlet obstruction (BOO) secondary to prostatic obstruction, and to assess it is a feasible option for many frail and elderly men unsuitable for surgery.

MATERIALS AND METHODS

We reviewed patients who underwent insertion of a Memokath stent for BOO over 17 years (January 1999 to December 2015) at one regional center over a long follow-up period (median, 7 years). Patients were selected if they had obstructive urinary symptoms or urinary retention with an indwelling catheter , and were ineligible for transurethral resection of the prostate (TURP) under general or spinal anesthesia. Primary outcomes assessed were the improvement in urinary symptoms and voiding parameters, as well as the ability to void spontaneously if catheterized, along with complications.

RESULTS

One hundred forty-four patients who presented with BOO or urinary retention had a Memokath stent inserted. Ninety patients (62.5%) had a successful stent insertion with a significant difference between the median preoperative (550 mL) and postoperative residual volume (80 mL, p<0.0001). Nearly two-thirds of men (64%) returned to unassisted voiding with no increased risk of complications over time. Fifty-four patients (37.5%) experienced stent failure. Main complications requiring stent removal or repositioning were migration, occlusion, refractory urinary retention and irritative voiding symptoms.

CONCLUSIONS

In elderly and frail men with BOO deemed unsuitable to undergo TURP, prostatic stent is a safe and practical alternative to long-term catheterization.

摘要

目的

报告我们使用热膨胀性金属前列腺内支架(Memokath)治疗因前列腺梗阻导致膀胱出口梗阻(BOO)患者的结果,并评估其是否是许多不适宜手术的虚弱和老年男性的可行选择。

材料和方法

我们回顾了在一个区域中心 17 年(1999 年 1 月至 2015 年 12 月)期间接受 Memokath 支架置入术治疗 BOO 的患者,随访时间较长(中位数为 7 年)。选择有梗阻性尿路症状或留置导尿管的尿潴留患者,且不符合全身或脊髓麻醉下经尿道前列腺切除术(TURP)的条件。主要评估的结果是尿路症状和排尿参数的改善,以及在导尿情况下自主排尿的能力,以及并发症。

结果

144 例出现 BOO 或尿潴留的患者接受了 Memokath 支架置入术。90 例(62.5%)患者支架置入成功,术前(550 毫升)和术后残余尿量(80 毫升,p<0.0001)中位数存在显著差异。近三分之二的男性(64%)恢复了无需辅助的排尿,且随着时间的推移并发症风险没有增加。54 例(37.5%)患者支架失败。需要移除或重新定位支架的主要并发症是迁移、阻塞、难治性尿潴留和刺激性排尿症状。

结论

对于被认为不适合接受 TURP 的有 BOO 的老年和虚弱男性,前列腺支架是长期留置导尿管的安全实用替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b72/5671965/3872adbce8c6/icu-58-447-g001.jpg

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