维生素D代谢及其对动脉粥样硬化的影响。
Vitamin D Metabolism and the Implications for Atherosclerosis.
作者信息
Bennett Amanda L, Lavie Carl J
机构信息
Department of Internal Medicine, Ochsner Clinic Foundation, New Orleans, LA, USA.
Department of Cardiovascular Disease, John Ochsner Heart and Vascular Institute, 1514 Jefferson Hwy, New Orleans, LA, USA, 70121.
出版信息
Adv Exp Med Biol. 2017;996:185-192. doi: 10.1007/978-3-319-56017-5_15.
Vitamin D levels and metabolism may play a role in the pathogenesis and treatment of atherosclerosis and subsequent cardiovascular health. Herein, we discuss both normal and disordered vitamin D metabolism as it pertains to atherosclerosis, and we review major clinical trials regarding vitamin D levels and effects of supplementation. Although there are no official recommendations for vitamin D as it applies to atherosclerosis, it is clear that these two entities are linked. Further study of the complex association between vitamin D and atherosclerosis, as well as the effects of supplementation, are recommended.
维生素D水平及代谢可能在动脉粥样硬化的发病机制、治疗以及后续心血管健康中发挥作用。在此，我们将讨论与动脉粥样硬化相关的正常及紊乱的维生素D代谢，并回顾关于维生素D水平及补充剂效果的主要临床试验。尽管尚无针对维生素D在动脉粥样硬化方面的官方推荐，但很明显这两者存在关联。建议进一步研究维生素D与动脉粥样硬化之间的复杂关联以及补充剂的效果。
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