低强度激光疗法对兔骨折愈合的影响。
Effect of low-level laser therapy on fracture healing in rabbits.
作者信息
Sarvestani Fahimeh Kamali, Dehno Nasrin Salehi, Nazhvani Seifollah Dehghani, Bagheri Mohammad Hadi, Abbasi Soheila, Khademolhosseini Yasaman, Gorji Elham
机构信息
School of rehabilitation, Shiraz University of Medical Sciences, Shiraz, Iran.
Rehabilitation Science Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
出版信息
Laser Ther. 2017 Sep 30;26(3):189-193. doi: 10.5978/islsm.17-OR-14.
BACKGROUND AND AIMS
The purpose of this study was to investigate the effect of low-level laser therapy (LLLT) on radial bone fracture gap healing in a rabbit model.
MATERIALS SUBJECTS AND METHODS
Thirty male white New Zealand rabbits under general anesthesia had a 3mm slice of radial bone surgically removed. Fifteen rabbits were treated by 830 nm laser at 4 J/cm and 15 were used as non-treated controls. Callus development was assessed by X-ray and radiographs every 7 days for 3 weeks.
RESULTS
Significant radiologic changes were observed in both groups against time (P > 0.001) or from week to week (P > 0.05). However, there was no statistical difference in radiologic scores after week 2 (P = 0.087) or week 3 (P = 0.077) between control and laser treated bone.
CONCLUSIONS
Findings suggest that in this study, laser treatment did not enhance callus formation nor reduce repair time of complete fracture of the radius in rabbits.
背景与目的
本研究旨在探讨低强度激光疗法（LLLT）对兔桡骨骨折间隙愈合的影响。
材料、对象与方法：30只雄性白色新西兰兔在全身麻醉下通过手术切除3毫米的桡骨切片。15只兔子接受波长830纳米、能量密度4焦耳/平方厘米的激光治疗，另外15只作为未治疗的对照组。在3周内，每隔7天通过X射线和X光片评估骨痂形成情况。
结果
两组在随时间推移（P > 0.001）或每周之间（P > 0.05）均观察到显著的放射学变化。然而，对照组和激光治疗组在第2周（P = 0.087）或第3周（P = 0.077）后的放射学评分无统计学差异。
结论
研究结果表明，在本研究中，激光治疗并未促进兔桡骨完全骨折的骨痂形成，也未缩短其修复时间。
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