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本文引用的文献

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Effect of low-level laser therapy on bone repair: a randomized controlled experimental study.低强度激光疗法对骨修复的影响：一项随机对照实验研究。
Lasers Med Sci. 2015 Apr;30(3):1061-8. doi: 10.1007/s10103-015-1710-0. Epub 2015 Jan 18.
2
Effect of low-level laser therapy on repair of the bone compromised by radiotherapy.低强度激光疗法对放疗所致骨损伤修复的影响。
Lasers Med Sci. 2014 Nov;29(6):1913-8. doi: 10.1007/s10103-014-1602-8. Epub 2014 Jun 10.
3
Comparison of the effects of low-level laser therapy and low-intensity pulsed ultrasound on the process of bone repair in the rat tibia.低强度激光疗法与低强度脉冲超声对大鼠胫骨骨修复过程影响的比较
Rev Bras Fisioter. 2011 May-Jun;15(3):200-5.
4
Comparative study of the effects of low-intensity pulsed ultrasound and low-level laser therapy on bone defects in tibias of rats.低强度脉冲超声和低水平激光治疗对大鼠胫骨骨缺损影响的对比研究。
Lasers Med Sci. 2010 Sep;25(5):727-32. doi: 10.1007/s10103-010-0772-2. Epub 2010 Jun 3.
5
Effects of low power laser irradiation on bone healing in animals: a meta-analysis.低强度激光照射对动物骨愈合的影响：荟萃分析。
J Orthop Surg Res. 2010 Jan 4;5:1. doi: 10.1186/1749-799X-5-1.
6
Effect of low-level laser therapy on the fracture healing process.低水平激光疗法对骨折愈合过程的影响。
Lasers Med Sci. 2010 Jan;25(1):73-7. doi: 10.1007/s10103-009-0670-7. Epub 2009 Apr 28.
7
Effect of lower-level laser therapy on rabbit tibial fracture.低强度激光疗法对兔胫骨骨折的影响。
Photomed Laser Surg. 2007 Dec;25(6):487-94. doi: 10.1089/pho.2006.2075.
8
Effect of low-level laser therapy on bone repair: histological study in rats.低强度激光疗法对骨修复的影响：大鼠组织学研究
Lasers Surg Med. 2007 Dec;39(10):788-96. doi: 10.1002/lsm.20585.
9
The effects of laser irradiation on osteoblast and osteosarcoma cell proliferation and differentiation in vitro.激光照射对体外成骨细胞和骨肉瘤细胞增殖及分化的影响。
Photomed Laser Surg. 2007 Aug;25(4):275-80. doi: 10.1089/pho.2007.2055.
10
Effects of laser irradiation on the release of basic fibroblast growth factor (bFGF), insulin like growth factor-1 (IGF-1), and receptor of IGF-1 (IGFBP3) from gingival fibroblasts.激光照射对牙龈成纤维细胞释放碱性成纤维细胞生长因子（bFGF）、胰岛素样生长因子-1（IGF-1）及IGF-1受体（IGFBP3）的影响。
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低强度激光疗法对兔骨折愈合的影响。

Effect of low-level laser therapy on fracture healing in rabbits.

作者信息

Sarvestani Fahimeh Kamali, Dehno Nasrin Salehi, Nazhvani Seifollah Dehghani, Bagheri Mohammad Hadi, Abbasi Soheila, Khademolhosseini Yasaman, Gorji Elham

机构信息

School of rehabilitation, Shiraz University of Medical Sciences, Shiraz, Iran.

Rehabilitation Science Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Laser Ther. 2017 Sep 30;26(3):189-193. doi: 10.5978/islsm.17-OR-14.

DOI:10.5978/islsm.17-OR-14
PMID:29133966
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5675909/
Abstract

BACKGROUND AND AIMS

The purpose of this study was to investigate the effect of low-level laser therapy (LLLT) on radial bone fracture gap healing in a rabbit model.

MATERIALS SUBJECTS AND METHODS

Thirty male white New Zealand rabbits under general anesthesia had a 3mm slice of radial bone surgically removed. Fifteen rabbits were treated by 830 nm laser at 4 J/cm and 15 were used as non-treated controls. Callus development was assessed by X-ray and radiographs every 7 days for 3 weeks.

RESULTS

Significant radiologic changes were observed in both groups against time (P > 0.001) or from week to week (P > 0.05). However, there was no statistical difference in radiologic scores after week 2 (P = 0.087) or week 3 (P = 0.077) between control and laser treated bone.

CONCLUSIONS

Findings suggest that in this study, laser treatment did not enhance callus formation nor reduce repair time of complete fracture of the radius in rabbits.

摘要

背景与目的

本研究旨在探讨低强度激光疗法（LLLT）对兔桡骨骨折间隙愈合的影响。

材料、对象与方法：30只雄性白色新西兰兔在全身麻醉下通过手术切除3毫米的桡骨切片。15只兔子接受波长830纳米、能量密度4焦耳/平方厘米的激光治疗，另外15只作为未治疗的对照组。在3周内，每隔7天通过X射线和X光片评估骨痂形成情况。

结果

两组在随时间推移（P > 0.001）或每周之间（P > 0.05）均观察到显著的放射学变化。然而，对照组和激光治疗组在第2周（P = 0.087）或第3周（P = 0.077）后的放射学评分无统计学差异。

结论

研究结果表明，在本研究中，激光治疗并未促进兔桡骨完全骨折的骨痂形成，也未缩短其修复时间。