视神经脊髓炎谱系疾病中的认知障碍：我们了解多少？
Cognitive impairment in neuromyelitis optica spectrum disorders: What do we know?
机构信息
Demyelinating Diseases Section, J.M. Ramos Mejía Hospital, Buenos Aires, Argentina.
Demyelinating Diseases Section, J.M. Ramos Mejía Hospital, Buenos Aires, Argentina.
出版信息
Mult Scler Relat Disord. 2017 Nov;18:225-229. doi: 10.1016/j.msard.2017.10.003. Epub 2017 Oct 6.
The aim of this study is to make a descriptive review of the bibliography available on cognitive dysfunction in patients with neuromyelitis optica spectrum disorders (NMOSD). We selected fifteen studies that quantitatively assess the relationship between NMOSD and one or more cognitive variables. Results showed that patients with NMOSD had a decrease in cognitive functions. Cognitive dysfunctions were found in 35-67% of patients with NMOSD, specifically in the attention, memory and information processing speed. Cognitive dysfunctions were found to relate to injuries in white matter as well as clinical variables and depression.
本研究旨在对神经脊髓炎谱系疾病（NMOSD）患者认知功能障碍的文献进行描述性综述。我们选择了 15 项定量评估 NMOSD 与一个或多个认知变量之间关系的研究。结果表明，NMOSD 患者的认知功能下降。NMOSD 患者中存在认知功能障碍的比例为 35-67%，具体表现为注意力、记忆力和信息处理速度受损。认知功能障碍与白质损伤、临床变量和抑郁有关。
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