• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Brucella Lipopolysaccharide and pathogenicity: The core of the matter.

作者信息

Smith Judith A

机构信息

a University of Madison School of Medicine and Public Health , Madison WI.

出版信息

Virulence. 2018 Jan 1;9(1):379-382. doi: 10.1080/21505594.2017.1395544.

DOI:10.1080/21505594.2017.1395544
PMID:29144201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7000210/
Abstract
摘要

相似文献

1
Brucella Lipopolysaccharide and pathogenicity: The core of the matter.布鲁氏菌脂多糖与致病性:问题的核心
Virulence. 2018 Jan 1;9(1):379-382. doi: 10.1080/21505594.2017.1395544.
2
The identification of wadB, a new glycosyltransferase gene, confirms the branched structure and the role in virulence of the lipopolysaccharide core of Brucella abortus.新糖基转移酶基因wadB的鉴定证实了流产布鲁氏菌脂多糖核心的分支结构及其在毒力中的作用。
Microb Pathog. 2014 Aug;73:53-9. doi: 10.1016/j.micpath.2014.06.002. Epub 2014 Jun 11.
3
The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition.布鲁氏菌属脂多糖核心作为一种盾牌,抵御先天免疫识别。
PLoS Pathog. 2012;8(5):e1002675. doi: 10.1371/journal.ppat.1002675. Epub 2012 May 10.
4
Lipopolysaccharide as a target for brucellosis vaccine design.脂多糖作为布鲁氏菌病疫苗设计的靶标。
Microb Pathog. 2013 May;58:29-34. doi: 10.1016/j.micpath.2012.11.011. Epub 2012 Dec 5.
5
Brucella abortus Induces the Premature Death of Human Neutrophils through the Action of Its Lipopolysaccharide.布鲁氏菌通过其脂多糖的作用诱导人类中性粒细胞过早死亡。
PLoS Pathog. 2015 May 6;11(5):e1004853. doi: 10.1371/journal.ppat.1004853. eCollection 2015 May.
6
Brucella lipopolysaccharide reinforced Salmonella delivering Brucella immunogens protects mice against virulent challenge.布鲁氏菌脂多糖增强递送布鲁氏菌免疫原的沙门氏菌可保护小鼠免受强毒株攻击。
Vet Microbiol. 2017 Jun;205:84-91. doi: 10.1016/j.vetmic.2017.05.012. Epub 2017 May 17.
7
Inflammatory response of TLR4 deficient spleen macrophages (CRL 2471) to Brucella abortus S19 and an isogenic ΔmglA deletion mutant.Toll样受体4缺陷型脾巨噬细胞(CRL 2471)对流产布鲁氏菌S19及同基因ΔmglA缺失突变体的炎症反应
Int J Med Microbiol. 2016 May;306(3):141-51. doi: 10.1016/j.ijmm.2016.02.006. Epub 2016 Feb 20.
8
The lipopolysaccharide of Brucella abortus BvrS/BvrR mutants contains lipid A modifications and has higher affinity for bactericidal cationic peptides.流产布鲁氏菌BvrS/BvrR突变体的脂多糖含有脂质A修饰,且对杀菌阳离子肽具有更高的亲和力。
J Bacteriol. 2005 Aug;187(16):5631-9. doi: 10.1128/JB.187.16.5631-5639.2005.
9
Live Brucella abortus rough vaccine strain RB51 stimulates enhanced innate immune response in vitro compared to rough vaccine strain RB51SOD and virulent smooth strain 2308 in murine bone marrow-derived dendritic cells.活布鲁氏菌粗糙疫苗株 RB51 刺激体外骨髓源性树突状细胞中增强的固有免疫反应,优于粗糙疫苗株 RB51SOD 和毒力光滑株 2308。
Vet Microbiol. 2011 Jan 10;147(1-2):75-82. doi: 10.1016/j.vetmic.2010.06.001. Epub 2010 Jun 10.
10
Studies in the pathology and pathogenesis of experimental brucellosis. I. A comparison of the pathogenicity of Brucella abortus, Brucella melitensis, and Brucella suis for guinea pigs.实验性布鲁氏菌病的病理学与发病机制研究。I. 流产布鲁氏菌、羊种布鲁氏菌和猪种布鲁氏菌对豚鼠致病性的比较。
J Infect Dis. 1951 Jul-Aug;89(1):76-86. doi: 10.1093/infdis/89.1.76.

引用本文的文献

1
Hybrid Whole Genomes of from Tunisian Animal Isolates: Virulence Factors, Antimicrobial Susceptibility, and Phylogeny.突尼斯动物分离株的混合全基因组:毒力因子、抗菌药敏性及系统发育
Microorganisms. 2025 Jul 12;13(7):1651. doi: 10.3390/microorganisms13071651.
2
Screening and characterization of nucleic acid aptamers targeting Brucella surface antigens: identification and analysis of their corresponding binding sites.靶向布鲁氏菌表面抗原的核酸适配体的筛选与鉴定:其相应结合位点的识别与分析
World J Microbiol Biotechnol. 2025 Jun 2;41(6):186. doi: 10.1007/s11274-025-04430-7.
3
triggers the differential expression of immunomodulatory lncRNAs in infected murine macrophages.触发感染的小鼠巨噬细胞中免疫调节性长链非编码RNA的差异表达。
Front Immunol. 2024 Feb 16;15:1352306. doi: 10.3389/fimmu.2024.1352306. eCollection 2024.
4
Lipopolysaccharides of S2 Impaired the Process of Decidualization in Early Pregnancy in Mice.S2 脂多糖损害了小鼠早孕时的蜕膜化进程。
Toxins (Basel). 2023 Nov 16;15(11):662. doi: 10.3390/toxins15110662.
5
Expression of Gene in the Placentas from Humans and Cows during Infection.在人类和牛的胎盘组织中感染时基因的表达。
Arch Razi Inst. 2022 Oct 31;77(5):1575-1586. doi: 10.22092/ARI.2022.358327.2192. eCollection 2022 Oct.
6
Immunosuppressive Mechanisms in Brucellosis in Light of Chronic Bacterial Diseases.从慢性细菌性疾病角度看布鲁氏菌病的免疫抑制机制
Microorganisms. 2022 Jun 21;10(7):1260. doi: 10.3390/microorganisms10071260.
7
Induction of TLR4/TLR2 Interaction and Heterodimer Formation by Low Endotoxic Atypical LPS.低内毒素非典型 LPS 诱导 TLR4/TLR2 相互作用和异源二聚体形成。
Front Immunol. 2022 Jan 24;12:748303. doi: 10.3389/fimmu.2021.748303. eCollection 2021.
8
Undercover Agents of Infection: The Stealth Strategies of T4SS-Equipped Bacterial Pathogens.携带感染物的卧底:配备 T4SS 的细菌病原体的隐秘策略。
Toxins (Basel). 2021 Oct 9;13(10):713. doi: 10.3390/toxins13100713.
9
Serological and molecular investigation of human brucellosis in participants of Famenin brucellosis cohort study, Hamadan, Iran.伊朗哈马丹法梅宁布鲁氏菌病队列研究参与者中人类布鲁氏菌病的血清学和分子学调查
Iran J Microbiol. 2021 Jun;13(3):319-324. doi: 10.18502/ijm.v13i3.6394.
10
When the Going Gets Rough: The Significance of Lipopolysaccharide Phenotype in Host-Pathogen Interactions.形势艰难时:脂多糖表型在宿主-病原体相互作用中的意义
Front Microbiol. 2021 Jul 15;12:713157. doi: 10.3389/fmicb.2021.713157. eCollection 2021.

本文引用的文献

1
Immunomodulatory properties of Brucella melitensis lipopolysaccharide determinants on mouse dendritic cells in vitro and in vivo.布鲁氏菌脂多糖决定簇对体外和体内小鼠树突状细胞的免疫调节特性。
Virulence. 2018 Jan 1;9(1):465-479. doi: 10.1080/21505594.2017.1386831.
2
Structural Studies of Lipopolysaccharide-defective Mutants from Brucella melitensis Identify a Core Oligosaccharide Critical in Virulence.来自羊种布鲁氏菌的脂多糖缺陷型突变体的结构研究确定了一种对毒力至关重要的核心寡糖。
J Biol Chem. 2016 Apr 1;291(14):7727-41. doi: 10.1074/jbc.M115.701540. Epub 2016 Feb 11.
3
Smooth to Rough Dissociation in Brucella: The Missing Link to Virulence.布鲁氏菌中从光滑型到粗糙型的解离:毒力缺失的环节
Front Cell Infect Microbiol. 2016 Jan 5;5:98. doi: 10.3389/fcimb.2015.00098. eCollection 2015.
4
Brucella spp. Virulence Factors and Immunity.布鲁氏菌属的毒力因子与免疫
Annu Rev Anim Biosci. 2016;4:111-27. doi: 10.1146/annurev-animal-021815-111326. Epub 2015 Dec 23.
5
CD8+ T cell exhaustion, suppressed gamma interferon production, and delayed memory response induced by chronic Brucella melitensis infection.慢性布鲁氏菌感染诱导的CD8 + T细胞耗竭、γ干扰素产生受抑制及记忆反应延迟。
Infect Immun. 2015 Dec;83(12):4759-71. doi: 10.1128/IAI.01184-15. Epub 2015 Sep 28.
6
Brucella abortus Induces the Premature Death of Human Neutrophils through the Action of Its Lipopolysaccharide.布鲁氏菌通过其脂多糖的作用诱导人类中性粒细胞过早死亡。
PLoS Pathog. 2015 May 6;11(5):e1004853. doi: 10.1371/journal.ppat.1004853. eCollection 2015 May.
7
Modulation of toll-like receptor 4. Insights from x-ray crystallography and molecular modeling.Toll样受体4的调控。来自X射线晶体学和分子建模的见解。
Curr Top Med Chem. 2014;14(23):2672-83. doi: 10.2174/1568026614666141215144831.
8
Improved immunogenicity of tetanus toxoid by Brucella abortus S19 LPS adjuvant.布鲁氏菌流产亚种S19脂多糖佐剂增强破伤风类毒素的免疫原性
Iran J Immunol. 2014 Sep;11(3):189-99.
9
Influence of Brucella abortus lipopolysaccharide as an adjuvant on the immunogenicity of HPV-16 L1VLP vaccine in mice.流产布鲁氏菌脂多糖作为佐剂对小鼠人乳头瘤病毒16型L1病毒样颗粒疫苗免疫原性的影响
Med Microbiol Immunol. 2015 Apr;204(2):205-13. doi: 10.1007/s00430-014-0356-z. Epub 2014 Sep 4.
10
The identification of wadB, a new glycosyltransferase gene, confirms the branched structure and the role in virulence of the lipopolysaccharide core of Brucella abortus.新糖基转移酶基因wadB的鉴定证实了流产布鲁氏菌脂多糖核心的分支结构及其在毒力中的作用。
Microb Pathog. 2014 Aug;73:53-9. doi: 10.1016/j.micpath.2014.06.002. Epub 2014 Jun 11.