Colistin Resistance of Isolated from Snakes in Taiwan.

This study included fifty-eight isolates of from the oral cavity of snakes that were recruited from clinical cases, captive and wild snakes. The minimum inhibitory concentrations (MICs) for the determination of susceptibility were identified by the broth microdilution method. Polymerase chain reaction (PCR) was employed to detect -lactamases genes. With regard to antipseudomonal antibiotics, the lowest nonsusceptible rates were in aztreonam (15%), piperacillin/tazobactam (12%), and amikacin (9%). The nonsusceptible rates were high in gentamicin (33%) and colistin (55%). Meanwhile, presented in 100% of isolates where , , and came at 94.8%, 89.7%, and 27.6%, respectively. Emergence of multidrug resistant (MDR) strains and colistin-resistant strains highlights the potential breach of public health as could be transmitted through either direct contact or indirect dissemination through the environment. This study reports that the highly resistant from snakes' oral cavity were discovered for the very first time in Taiwan.