切尔诺贝利事故27年后土耳其东部甲状腺癌的分布情况。

Distribution of Thyroid Cancer in the Eastern Part of Turkey 27 Years After the Chernobyl Accident.

作者信息

Sahin Serap Baydur, Yucel Ahmet Fikret, Gucer Hasan, Pergel Ahmet, Bedir Recep, Aydin Ibrahim, Sehitoglu Ibrahim, Sahin Dursun Ali, Sahin Osman Zikrullah

机构信息

Department of Endocrinology and Metabolism Disease, Recep Tayyip Erdogan University, Rize, Turkey.

Department of Surgery, Recep Tayyip Erdogan University, Rize, Turkey.

出版信息

World J Oncol. 2013 Dec;4(6):230-234. doi: 10.4021/wjon726w. Epub 2014 Jan 16.

DOI:10.4021/wjon726w

PMID:29147362

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5649847/

Abstract

BACKGROUND

The Chernobyl accident caused widespread effects across Europe and huge areas where radiocontaminated. The effects of the Chernobyl accident on thyroid cancer have been investigated in most European countries. According to the data of the Turkish Atomic Energy Authority, the eastern part of the Black Sea region was the most radiocontaminated area in Turkey at the time of Chernobyl accident. We therefore aimed to examine the data of thyroid cancers at our center, Rize city which is located in the eastern Black Sea region.

METHODS

This retrospective study included the patients with histologically proven thyroid cancer at our center between January 2008 and May 2012. Pathologic examinations of thyroidectomy materials were reviewed. We evaluated patients' age, gender, size of the primary tumor (all sizes, < 1 cm, 1 - 2.9 cm, 3 - 3.9 cm and ≥ 4 cm), multicentricity, histologic subtypes of thyroid cancer, the presence of lymphatic, vascular, capsule and the extrathyroidal invasion.

RESULTS

Five hundred and forty-seven of the 3,556 patients were diagnosed with thyroid cancer. The mean age of the patients was 49.31 ± 0.49 years. The histopathologic diagnosis of patients was papillary carcinoma in 533 (97.4%) and the tumor size was < 1 cm in 53.6% of the patients. The presence of multicentricity was detected in 47% of the patients.

CONCLUSION

The portion of thyroid carcinomas in all thyroidectomies was 15.4% in our institution 27 years after the Chernobyl accident.

摘要

背景

切尔诺贝利事故在欧洲造成了广泛影响，大片地区受到放射性污染。大多数欧洲国家都对切尔诺贝利事故对甲状腺癌的影响进行了调查。根据土耳其原子能管理局的数据，在切尔诺贝利事故发生时，黑海地区东部是土耳其放射性污染最严重的地区。因此，我们旨在研究位于黑海地区东部的里泽市我们中心的甲状腺癌数据。

方法

这项回顾性研究纳入了2008年1月至2012年5月期间在我们中心经组织学证实为甲状腺癌的患者。对甲状腺切除材料的病理检查进行了复查。我们评估了患者的年龄、性别、原发肿瘤大小（所有大小、<1cm、1 - 2.9cm、3 - 3.9cm和≥4cm）、多中心性、甲状腺癌的组织学亚型、淋巴管、血管、包膜和甲状腺外侵犯情况。