Klein B E, Moss S E, Magli Y L, Klein R, Hoyer C, Johnson J
Department of Ophthalmology, University of Wisconsin Medical School, Madison 53792.
Invest Ophthalmol Vis Sci. 1989 Feb;30(2):304-9.
Increased cupping of the optic disc is considered to be an indication of pressure-related damage of the optic nerve. This paper explores the relationship of intraocular pressure and cupping in persons with diabetes mellitus, a group of people whose optic nerves may be more susceptible to the effects of intraocular pressure. Stereoscopic fundus photographs of the seven standard fields were obtained in all persons participating in the Wisconsin Epidemiologic Study of Diabetic Retinopathy at the time of the initial prevalence survey. Measurements of disc and cup diameters in the vertical and horizontal meridia were made by two trained graders. Cup-to-disc ratios were computed for both diameters of each eye and the mean of the two gradings was used. A history of glaucoma was significantly associated with larger cup-to-disc ratios at the prevalence examination. Cup-to-disc ratios were not larger in those with high IOP, nor in those who had panretinal photocoagulation.
视盘杯状凹陷增加被认为是视神经压力相关损伤的一个指标。本文探讨了糖尿病患者眼内压与杯状凹陷的关系，糖尿病患者的视神经可能对视内压的影响更敏感。在威斯康星糖尿病视网膜病变流行病学研究的初始患病率调查时，对所有参与研究的人员获取了七个标准视野的立体眼底照片。由两名经过培训的分级人员测量垂直和水平子午线方向的视盘和视杯直径。计算每只眼睛两个直径的杯盘比，并使用两次分级的平均值。在患病率检查中，青光眼病史与较大的杯盘比显著相关。高眼压患者和接受全视网膜光凝治疗的患者的杯盘比并不更大。
