Zyoud Sa'ed H, Al-Jabi Samah W, Sweileh Waleed M, Arandi Diana A, Dabeek Sujood A, Esawi Hiba H, Atyeh Remà H, Abu-Ali Hadeel A, Sleet Yazan I, Abd-Alfatah Baraa M, Awang Rahmat
Department of Clinical and Community Pharmacy, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
WHO Collaborating Centre for Drug Information, National Poison Centre, Universiti Sains Malaysia (USM), Penang, Malaysia.
J Clin Transl Endocrinol. 2015 Mar 31;2(2):66-71. doi: 10.1016/j.jcte.2015.03.002. eCollection 2015 Jun.
The aims of the current study were to assess the association between health-related quality of life (HRQoL) and treatment satisfaction in a sample of diabetic patients from Palestine, and to determine the influence of socio-demographic and clinical factors on HRQoL.
It was a cross-sectional study performed during the period June 2013 to October 2013. The Arabic version of Treatment Satisfaction Questionnaire for Medication (TSQM 1.4) was used to assess treatment satisfaction, and the Arabic version of European Quality of Life scale (EQ-5D-5L) was used to assess HRQoL. Multiple linear regression was used to estimate which variables were the most important related to HRQoL.
A total of 385 diabetic patients were included. There were modest positive correlations between the total score on the Overall Satisfaction domain and EQ-5D-5L ( = 0.14; = 0.005). After adjusting multiple covariates by multiple linear regression, the association between the Overall Satisfaction and HRQoL was not statistically significant ( = 0.075); ( = 0.495; adjusted = 0.245; = 10.3; df = 12; < 0.001). The results showed that elderly patients, being unemployed, and number of comorbid diseases, were significantly associated with HRQoL.
Overall, these results indicate that elderly patients, being unemployed, and those with comorbid diseases, are independent risk factors for poor HRQoL. Furthermore, it emerges that HRQoL and treatment satisfaction are both probably influenced by socio-demographic and clinical characteristics. In fact, to improve diabetic patients' quality of life, elderly patients were recommended to receive more attention in their health and economic status.
本研究旨在评估巴勒斯坦糖尿病患者样本中健康相关生活质量(HRQoL)与治疗满意度之间的关联,并确定社会人口统计学和临床因素对HRQoL的影响。
这是一项在2013年6月至2013年10月期间进行的横断面研究。采用阿拉伯语版的药物治疗满意度问卷(TSQM 1.4)评估治疗满意度,采用阿拉伯语版的欧洲生活质量量表(EQ-5D-5L)评估HRQoL。使用多元线性回归来估计哪些变量与HRQoL最为相关。
共纳入385名糖尿病患者。总体满意度领域的总分与EQ-5D-5L之间存在适度的正相关(r = 0.14;p = 0.005)。通过多元线性回归调整多个协变量后,总体满意度与HRQoL之间的关联无统计学意义(β = 0.075);(p = 0.495;调整后的β = 0.245;F = 10.3;df = 12;p < 0.001)。结果显示,老年患者、失业者和合并症数量与HRQoL显著相关。
总体而言,这些结果表明老年患者、失业者和合并症患者是HRQoL较差的独立危险因素。此外,HRQoL和治疗满意度可能都受到社会人口统计学和临床特征的影响。事实上,为了提高糖尿病患者的生活质量,建议对老年患者的健康和经济状况给予更多关注。