Pilet-Nayel Marie-Laure, Moury Benoît, Caffier Valérie, Montarry Josselin, Kerlan Marie-Claire, Fournet Sylvain, Durel Charles-Eric, Delourme Régine
Institute for Genetics, Environment and Plant Protection (INRA), UMR 1349, Leu Rheu, France.
PISOM, UMT INRA-Terres Inovia, Le Rheu, France.
Front Plant Sci. 2017 Oct 27;8:1838. doi: 10.3389/fpls.2017.01838. eCollection 2017.
Quantitative resistance has gained interest in plant breeding for pathogen control in low-input cropping systems. Although quantitative resistance frequently has only a partial effect and is difficult to select, it is considered more durable than major resistance (R) genes. With the exponential development of molecular markers over the past 20 years, resistance QTL have been more accurately detected and better integrated into breeding strategies for resistant varieties with increased potential for durability. This review summarizes current knowledge on the genetic inheritance, molecular basis, and durability of quantitative resistance. Based on this knowledge, we discuss how strategies that combine major R genes and QTL in crops can maintain the effectiveness of plant resistance to pathogens. Combining resistance QTL with complementary modes of action appears to be an interesting strategy for breeding effective and potentially durable resistance. Combining quantitative resistance with major R genes has proven to be a valuable approach for extending the effectiveness of major genes. In the plant genomics era, improved tools and methods are becoming available to better integrate quantitative resistance into breeding strategies. Nevertheless, optimal combinations of resistance loci will still have to be identified to preserve resistance effectiveness over time for durable crop protection.
在低投入种植系统中，数量抗性在植物抗病育种方面受到了关注。尽管数量抗性通常只有部分效果且难以选择，但它被认为比主要抗性（R）基因更持久。随着过去20年分子标记的指数级发展，抗性QTL已被更准确地检测到，并更好地整合到具有更高持久潜力的抗病品种育种策略中。本综述总结了关于数量抗性的遗传遗传、分子基础和持久性的当前知识。基于这些知识，我们讨论了作物中结合主要R基因和QTL的策略如何能够维持植物对病原体的抗性有效性。将抗性QTL与互补作用模式相结合似乎是培育有效且可能持久抗性的一个有趣策略。将数量抗性与主要R基因相结合已被证明是延长主要基因有效性的一种有价值方法。在植物基因组学时代，越来越多的改进工具和方法可用于更好地将数量抗性整合到育种策略中。然而，仍需确定抗性位点的最佳组合，以便随着时间的推移保持抗性有效性，实现持久的作物保护。
