Gottlieb M S, Pickle L W, Blot W J, Fraumeni J F
J Natl Cancer Inst. 1979 Nov;63(5):1131-7.
In a search for etiologic clues, a review was made of death certificates of residents in a cluster of Louisiana parishes, mainly in the southern part of the state, where lung cancer mortality was high. A comparison of the statements on occupation for 3,327 patients with lung cancer and those of 3,327 controls (matched by sex, race, age, and parish of residence) during 1960-75 revealed an approximately twofold excess risk associated with transportation equipment manufacture, mainly shipbuilding, and the fishing industry. Smaller elevations of lung cancer risk were found among older men who had been employed in petroleum exploration and production and among male and female residents of towns where the petroleum industry was a major employer. In addition, Acadian ancestry was associated with a higher risk of lung cancer among older male and female residents.
为寻找病因线索，对路易斯安那州一群教区（主要位于该州南部，肺癌死亡率较高）居民的死亡证明进行了审查。对1960年至1975年间3327例肺癌患者与3327例对照者（按性别、种族、年龄和居住教区匹配）的职业陈述进行比较发现，与运输设备制造（主要是造船）和渔业相关的风险大约高出两倍。在曾从事石油勘探和生产工作的老年男性以及石油行业为主要雇主的城镇的男性和女性居民中，肺癌风险有较小程度的升高。此外，阿卡迪亚血统与老年男性和女性居民中较高的肺癌风险相关。
