Sjögren E, Ruiz-Palacios G, Kaijser B
Department of Clinical Bacteriology, University of Göteborg, Sweden.
Epidemiol Infect. 1989 Feb;102(1):47-57. doi: 10.1017/s0950268800029678.
The presence of different Campylobacter jejuni serotypes in Swedish patients with diarrhoea and in Mexican patients with or without diarrhoea was investigated with special reference to repeated isolations during the course of infection and to symptomatic and asymptomatic episodes. The study included 136 C. jejuni isolates from 62 Mexican children and 173 isolates from 68 Swedish patients. The bacteria were serotyped for heat-stable (HS) and heat-labile (HL) antigen. Swedish patients, all with symptoms, were in general only infected with one serotype and were rarely reinfected. Mexican patients on the other hand were in general infected with mixed serotypes and frequently reinfected without symptoms with new, different serotypes, a finding which is in concordance with a theory of an induced immunity to surface antigens.
对瑞典腹泻患者以及墨西哥有无腹泻症状患者体内不同空肠弯曲菌血清型进行了调查,特别关注感染过程中的重复分离情况以及有症状和无症状发作情况。该研究纳入了来自62名墨西哥儿童的136株空肠弯曲菌分离株以及来自68名瑞典患者的173株分离株。对这些细菌进行了热稳定(HS)和热不稳定(HL)抗原的血清分型。瑞典患者均有症状,一般仅感染一种血清型,很少再次感染。另一方面,墨西哥患者通常感染混合血清型,且经常无症状地再次感染新的、不同的血清型,这一发现与表面抗原诱导免疫理论相符。