Safarabadi Mehdi, Ghaznavi-Rad Ehsanollah, Pakniyat Abdolghader, Rezaie Korosh, Jadidi Ali
Department of Nursing, Arak University of Medical Sciences, Arak, Iran.
Molecular Research Center, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran.
Iran J Nurs Midwifery Res. 2017 Nov-Dec;22(6):481-485. doi: 10.4103/ijnmr.IJNMR_92_16.
Providing intubated patients admitted to the intensive care units with oral healthcare is one of the main tasks of nurses in order to prevent Ventilator-Associated Pneumonia (VAP). This study aimed at comparing the effects of two mouthwash solutions (echinacea and chlorhexidine) on the oral microbial flora of patients hospitalized in the intensive care units.
In this clinical trial, 70 patients aged between18 and 65 years undergoing tracheal intubation through the mouth in three hospitals in Arak, were selected using simple random sampling and were randomly divided into two groups: the intervention group and the control group. The oral health checklist was used to collect the data (before and after the intervention). The samples were obtained from the orally intubated patients and were then cultured in selective media. Afterwards, the aerobic microbial growth was investigated in all culture media. The data were analyzed using SPSS software.
The microbial flora in the echinacea group significantly decreased after the intervention ( < 0.0001) and it was also the case withmicrobial flora of the patients in the chlorhexidine group ( < 0.001). After 4 days, the oral microbial flora of the patients in the intervention group was lower than that of the patients in the control group ( < 0.001).
The results showed that the echinacea solution was more effective in decreasing the oral microbial flora of patients in the intensive care unit. Given the benefits of the components of the herb Echinacea, it can be suggested as a viable alternative to chlorhexidine.
为重症监护病房的插管患者提供口腔护理是护士的主要任务之一，以预防呼吸机相关性肺炎（VAP）。本研究旨在比较两种漱口液（紫锥菊和氯己定）对重症监护病房住院患者口腔微生物群的影响。
在这项临床试验中，采用简单随机抽样法，选取了阿拉克市三家医院70例年龄在18至65岁之间经口气管插管的患者，并将其随机分为两组：干预组和对照组。使用口腔健康检查表收集数据（干预前后）。从经口插管患者处采集样本，然后在选择性培养基中培养。之后，在所有培养基中研究需氧微生物生长情况。使用SPSS软件对数据进行分析。
干预后紫锥菊组的微生物群显著减少（<0.0001），氯己定组患者的微生物群也是如此（<0.001）。4天后，干预组患者的口腔微生物群低于对照组患者（<0.001）。
结果表明，紫锥菊溶液在减少重症监护病房患者口腔微生物群方面更有效。鉴于紫锥菊草药成分的益处，它可以被建议作为氯己定的可行替代品。
