Chen Yu, Fingler Jeff, Fraser Scott E
Translational Imaging Center, University of Southern California, Los Angeles, CA 90089, USA.
Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA.
Biomed Opt Express. 2017 Oct 26;8(11):5267-5281. doi: 10.1364/BOE.8.005267. eCollection 2017 Nov 1.
Shaping methods that are commonly used in Fourier-domain optical coherence tomography (FD-OCT) can suppress sidelobe artifacts in the axial direction, but they typically broaden the mainlobe of the point spread function (PSF) and reduce the axial resolution. To improve OCT image quality without this tradeoff, we have developed a multi-shaping technique that reduces the axial sidelobe magnitude dramatically and achieves better axial resolution than conventional shaping methods. This technique is robust and compatible in various FD-OCT imaging systems. Testing of multi-shaping in three experimental settings shows that it reduced the axial sidelobe contribution by more than 8 dB and improved the contrast to noise by at least 30% and up to three-fold. Multi-shaping enables accurate image analysis and is potentially useful in many OCT applications.
傅里叶域光学相干断层扫描(FD - OCT)中常用的整形方法可以抑制轴向方向上的旁瓣伪像,但它们通常会拓宽点扩散函数(PSF)的主瓣并降低轴向分辨率。为了在不进行这种权衡的情况下提高OCT图像质量,我们开发了一种多整形技术,该技术可显著降低轴向旁瓣幅度,并实现比传统整形方法更好的轴向分辨率。该技术在各种FD - OCT成像系统中都很稳健且兼容。在三种实验设置下对多整形进行的测试表明,它将轴向旁瓣贡献降低了超过8 dB,并将对比度噪声提高了至少30%,最高可达三倍。多整形能够实现准确的图像分析,并且在许多OCT应用中可能很有用。