Quigley Harry A
Glaucoma Center of Excellence, Wilmer Eye Institute, Johns Hopkins School of Medicine, Johns Hopkins Hospital, Wilmer 122, 600 N Wolfe Street, Baltimore, MD, 21287, USA.
Methods Mol Biol. 2018;1695:1-10. doi: 10.1007/978-1-4939-7407-8_1.
This chapter provides an overview over the use of animal models in glaucoma research from a historical perspective. Strengths and limitations of various models are considered, and the challenges of translating results in animal experiments to successful clinical trials in humans are discussed.
本章从历史角度概述了动物模型在青光眼研究中的应用。文中考虑了各种模型的优缺点,并讨论了将动物实验结果转化为人类成功临床试验所面临的挑战。