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中国北京一般人群中短链和中链氯化石蜡的体外接触。

External Exposure to Short- and Medium-Chain Chlorinated Paraffins for the General Population in Beijing, China.

机构信息

State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences , Beijing 100085, China.

University of Chinese Academy of Sciences , Beijing 100049, China.

出版信息

Environ Sci Technol. 2018 Jan 2;52(1):32-39. doi: 10.1021/acs.est.7b04657. Epub 2017 Dec 13.

DOI:10.1021/acs.est.7b04657
PMID:29190090
Abstract

Chlorinated paraffins (CPs) are a class of compounds that are currently produced and used in large amounts in commercial products worldwide. In this study, food, indoor air, indoor dust, and drinking water samples were collected to evaluate the external exposure levels of CPs and possible pathway for the general population in Beijing, China. Short chain CPs (SCCPs) and medium chain CPs (MCCPs) in 199 samples were analyzed using a gas chromatography tandem time-of-flight high-resolution mass spectrometry (GC-TOF-HR-MS) method. High levels of CPs were observed in the indoor environment from residential houses, offices, and student dormitories. The geometric mean concentrations (GM) of ∑SCCPs and ∑MCCPs in indoor dust were 92 μg g and 82 μg g, respectively, while in indoor air, the concentrations were 80 ng m and 3.4 ng m, respectively. The GM of ∑SCCPs and ∑MCCPs in the diet were 83 ng g dry weight (dw) and 56 ng g dw, respectively. The most important external exposure routes to CPs to the general populations in Beijing were food intake and indoor dust ingestion. Indoor dust and indoor air posed higher risks for toddlers and infants than for adults.

摘要

短链氯化石蜡(SCCPs)和中链氯化石蜡(MCCPs)在 199 个样本中采用气相色谱串联飞行时间高分辨率质谱法(GC-TOF-HR-MS)进行了分析。

室内环境中,居民住宅、办公室和学生宿舍的 SCCPs 和 MCCPs 含量较高。室内灰尘中∑SCCPs 和∑MCCPs 的几何平均浓度(GM)分别为 92μg/g 和 82μg/g,而室内空气中的浓度分别为 80ng/m 和 3.4ng/m。饮食中∑SCCPs 和∑MCCPs 的 GM 分别为 83ng/g 干重(dw)和 56ng/g dw。对北京普通人群而言,摄入食物和吞食室内灰尘是接触 SCCPs 和 MCCPs 的最重要途径。室内灰尘和室内空气对幼儿和婴儿的危害比成年人更高。

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