Shrestha Ananta
Department of Hepatology, The Liver Clinic, Liver Foundation Nepal, Tripureshwor, Kathmandu, Nepal.
Euroasian J Hepatogastroenterol. 2016 Jan-Jun;6(1):59-61. doi: 10.5005/jp-journals-10018-1169. Epub 2016 Jul 9.
Over the last four decades, the diagnosis and therapy of viral hepatitis has evolved substantially all over the world. Although Nepal is a developing nation, it has been keeping pace with these developments in terms of the implementation of diagnostic and therapeutic strategies. However, because of a lack of infrastructure and logistics, Nepal still depends on its neighboring countries for molecular diagnostics in viral hepatitis B and C. Though most of the recent antivirals for hepatitis B and directly acting antivirals for hepatitis C are available at a highly subsidized cost, affordability still remains an issue. A lack of comprehensive national program for hepatitis B and C has been a major barrier for access to health care in patients with chronic viral hepatitis. Similarly, hepatitis E still remains an important public health issue with major epidemics at periodic intervals. Recent developments in understanding hepatitis E virus have unveiled important aspects of the virus, particularly with regard to why these epidemics occur. In this manuscript we try to elaborate the evolution in understanding, diagnosing, and treating viral hepatitis in Nepal.
Shrestha A. Viral Hepatitis in Nepal: Past, Present, and Future. Euroasian J Hepato-Gastroenterol 2016;6(1):59-61.
在过去的四十年里，全球病毒性肝炎的诊断和治疗有了显著发展。尼泊尔虽是一个发展中国家，但在诊断和治疗策略的实施方面一直紧跟这些发展步伐。然而，由于缺乏基础设施和物流条件，尼泊尔在乙型和丙型病毒性肝炎的分子诊断方面仍依赖邻国。尽管近期大多数用于治疗乙型肝炎的抗病毒药物以及用于治疗丙型肝炎的直接抗病毒药物都以高额补贴的价格提供，但可承受性仍然是一个问题。缺乏针对乙型和丙型肝炎的全面国家计划一直是慢性病毒性肝炎患者获得医疗保健的主要障碍。同样，戊型肝炎仍然是一个重要的公共卫生问题，会定期爆发大规模疫情。最近对戊型肝炎病毒的认识进展揭示了该病毒的重要方面，特别是关于这些疫情为何发生的原因。在本手稿中，我们试图阐述尼泊尔在病毒性肝炎的认识、诊断和治疗方面的演变。
什雷斯塔 A. 尼泊尔的病毒性肝炎：过去、现在和未来。《欧亚肝脏胃肠病学杂志》2016 年；6(1):59 - 61。
