Roman Fabian, Iturry Mónica, Rojas Galeno, Barceló Ernesto, Buschke Herman, Allegri Ricardo F
Center for Aging and Memory Research, Hospital General Abel Zubizarreta (GCABA), Buenos Aires, Argentina.
University Corporation of the Coast (CUC), Barranquilla, Colombia.
Dement Neuropsychol. 2016 Jul-Sep;10(3):217-226. doi: 10.1590/S1980-5764-2016DN1003008.
"Forgetfulness" is frequent in normal aging and characteristic of the early stages of dementia syndromes. The episodic memory test is central for detecting amnestic mild cognitive impairment (MCI). The Memory Binding Test (MBT) is a simple, easy and brief memory test to detect the early stage of episodic memory impairment.
To validate the Argentine version of the MBT in a Latin American population and to estimate the diagnostic accuracy as a tool for early detection of MCI.
88 subjects (46 healthy controls and 42 patients with amnestic MCI) matched for age and educational level were evaluated by an extensive neuropsychological battery and the memory binding test.
A significantly better performance was detected in the control group; all MBT scales were predictive of MCI diagnosis (p<.01). The MBT showed high sensitivity (69%) and high specificity (88%), with a PPV of 93% and a NPV of 55% for associative paired recall. A statistically significant difference (c=14,164, p<.001) was obtained when comparing the area under the curve (AUC) of the MBT (0.88) and the MMSE (0.70).
The Argentine version of the MBT correlated significantly with the MMSE and the memory battery and is a useful tool in the detection of MCI. The operating characteristics of the MBT are well suited, surpassing other tests commonly used for detecting MCI.
“健忘”在正常衰老过程中很常见，也是痴呆综合征早期阶段的特征。情景记忆测试是检测遗忘型轻度认知障碍（MCI）的核心。记忆绑定测试（MBT）是一种简单、便捷的简短记忆测试，用于检测情景记忆障碍的早期阶段。
在拉丁美洲人群中验证MBT的阿根廷版本，并评估其作为早期检测MCI工具的诊断准确性。
对88名年龄和教育水平相匹配的受试者（46名健康对照者和42名遗忘型MCI患者）进行了广泛的神经心理学测试和记忆绑定测试。
对照组的表现明显更好；所有MBT量表都可预测MCI诊断（p<0.01）。MBT显示出高敏感性（69%）和高特异性（88%），关联配对回忆的阳性预测值为93%，阴性预测值为55%。比较MBT（0.88）和MMSE（0.70）的曲线下面积（AUC）时，获得了统计学上的显著差异（c=14,164，p<0.001）。
MBT的阿根廷版本与MMSE和记忆测试电池显著相关，是检测MCI的有用工具。MBT的操作特性非常合适，优于其他常用于检测MCI的测试。
