Department of Chemistry, Indian Institute of Science Education and Research Pune , Dr. Homi Bhabha Road, Pune 411 008, Maharashtra, India.
Org Lett. 2018 Jan 5;20(1):4-7. doi: 10.1021/acs.orglett.7b02544. Epub 2017 Dec 13.
A series of cell-permeable esterase-sensitive sulfonates that undergo self-immolation to produce sulfur dioxide (SO), a gaseous pollutant with new and emerging biological roles, is reported. These compounds should facilitate the study SO biology and will lay the platform for newer stimuli-responsive donors of this gas.
本文报道了一系列具有细胞通透性的酯酶敏感磺酸盐,这些磺酸盐通过自我燃烧产生二氧化硫(SO),SO 是一种具有新的和新兴生物学作用的气态污染物。这些化合物应该有助于研究 SO 的生物学,并为这种气体的新型刺激响应供体奠定平台。