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Introduction to the interleukin-1 family of cytokines and receptors: Drivers of innate inflammation and acquired immunity.

作者信息

Dinarello Charles A

机构信息

Department of Medicine, University of Colorado, Aurora, CO, USA.

Department of Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

出版信息

Immunol Rev. 2018 Jan;281(1):5-7. doi: 10.1111/imr.12624.

Abstract
摘要

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The role of the interleukin-1 family in trained immunity.
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Autophagy limits activation of the inflammasomes.
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Interleukin 1 gene polymorphism and susceptibility to disease.
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The NLRC4 Inflammasome.
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IL-1 and IL-1 regulatory pathways in cancer progression and therapy.
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Overview of the IL-1 family in innate inflammation and acquired immunity.
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Regulation and function of interleukin-36 cytokines.
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Interleukin-33 (IL-33): A nuclear cytokine from the IL-1 family.
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