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委内瑞拉三个地区的糖尿病患病率。VEMSOLS研究结果。

Prevalence of diabetes in three regions of Venezuela. The VEMSOLS study results.

作者信息

Nieto-Martínez Ramfis, Mechanick Jeffrey I, Brajkovich Imperia, Ugel Eunice, Risques Alejandro, Florez Hermes, González-Rivas Juan Pablo

机构信息

Department of Physiology, School of Medicine, University Centro-Occidental "Lisandro Alvarado" (UCLA), Barquisimeto, Venezuela; Cardio-Metabolic Unit 7, Barquisimeto, Venezuela; Geriatric Research, Education, and Clinical Center (GRECC), Miami VA Healthcare System, Miami, FL, USA; South Florida Veterans Affairs Foundation for Research & Education, Miami, USA.

Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

Prim Care Diabetes. 2018 Apr;12(2):126-132. doi: 10.1016/j.pcd.2017.11.005. Epub 2017 Dec 14.

DOI:10.1016/j.pcd.2017.11.005
PMID:29249672
Abstract

OBJECTIVE

The prevalence of diabetes in multiple regions of Venezuela is unknown. To determine the prevalence of diabetes in five populations from three regions of Venezuela.

METHODS

During 2006-2010, 1334 subjects ≥20years were selected by multistage stratified random sampling from all households from 3 regions of Venezuela. Anthropometric measurements and biochemical analysis were obtained. Statistical methods were calculated using SPSS 20 software.

FINDINGS

Mean (SE) age was 44.8 years (0.39) and 68.5% were females. The prevalence of diabetes was 8.3% (95% CI, 6.9%-10.0%), higher in men than women (11.2% and 7.0% respectively; p=0.01). The prevalence adjusted by age and gender was 8.0% (95% CI, 6.9%-9.9%). This figure increased with age, with the lowest prevalence in the 20-29year old group (1.8% [95% CI, 0.6%-4.8%]) and the highest in the oldest group (26.8% [95% CI, 16.2%-40.5%]). Subjects with overweight or obesity had no increased risk of diabetes compared with those with normal weight. However, in women, the presence of abdominal obesity was associated with an increase of the risk of diabetes by 77% (OR 1.77 [95% CI, 1.1%-2.9%]). The prevalence of prediabetes was 14.6% (95% CI, 12.8%-16.7%), and only 48.2% were aware of their diabetes condition.

CONCLUSION

In this study, 8.3% of the subjects had diabetes and 14.6% prediabetes. Less than half of the subjects with diabetes were aware of their condition. These results point to a major public health problem, requiring the implementation of diabetes prevention programs.

摘要

目的

委内瑞拉多个地区的糖尿病患病率未知。旨在确定委内瑞拉三个地区五个人口群体中的糖尿病患病率。

方法

在2006年至2010年期间,通过多阶段分层随机抽样从委内瑞拉三个地区的所有家庭中选取了1334名年龄≥20岁的受试者。进行了人体测量和生化分析。使用SPSS 20软件进行统计方法计算。

研究结果

平均(标准误)年龄为44.8岁(0.39),女性占68.5%。糖尿病患病率为8.3%(95%置信区间,6.9%-10.0%),男性高于女性(分别为11.2%和7.0%;p=0.01)。经年龄和性别调整后的患病率为8.0%(95%置信区间,6.9%-9.9%)。这一数字随年龄增长而增加,在20-29岁年龄组中患病率最低(1.8%[95%置信区间,0.6%-4.8%]),在最年长组中最高(26.8%[95%置信区间,16.2%-40.5%])。超重或肥胖受试者患糖尿病的风险与体重正常者相比并未增加。然而,在女性中,腹部肥胖与糖尿病风险增加77%相关(比值比1.77[95%置信区间,1.1%-2.9%])。糖尿病前期患病率为14.6%(95%置信区间,12.8%-16.7%),只有48.2%的糖尿病患者知晓自己的病情。

结论

在本研究中,8.3%的受试者患有糖尿病,14.6%患有糖尿病前期。不到一半的糖尿病患者知晓自己的病情。这些结果表明存在一个重大的公共卫生问题,需要实施糖尿病预防计划。

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